首页|开颅手术后深静脉血栓形成的危险因素

开颅手术后深静脉血栓形成的危险因素

扫码查看
目的 探讨开颅手术后深静脉血栓(DVT)形成的危险因素。方法 回顾性收集 2019 年 1 月~2022 年 12 月在江苏省人民医院神经外科接受开颅手术治疗的患者 202 例的数据资料。根据患者术后是否发生DVT进行分组,未发生DVT的为对照组(n=160),发生DVT的为观察组(n=42)。描述全部患者的临床资料情况,分析开颅手术后深静脉血栓形成的独立影响因素,采用logistic回归模型进行开颅术后深静脉血栓形成的预测效果分析。结果 202 例患者中 42 例患者发生DVT,DVT发生率为 20。79%。单因素分析结果中显示,两组患者的失血量、术后绝对卧床时间长度、凝血因子功能亢进比例数据差异具有统计学意义(P<0。05)。多因素分析结果显示,凝血因子功能亢进、失血量较大、术后绝对卧床时间长度较长是开颅手术后发生DVT的独立危险因素(P<0。05)。利用多因素模型以及各独立影响因素对开颅手术后发生DVT进行预测,最佳截断值分别为 526。42 ml、9。78 d、0。50、27。15%,ROC曲线下面积分别为 0。763、0。859、0。730、0。948,约登指数分别为62。41%、57。95%、46。04%、82。47%。结论 开颅手术患者在术后发生DVT的风险较高,通过危险因素的分析仪预测模型的建立,可以更好对该种情况进行防控,有助于降低患者的风险,提升手术成功率。
Risk factors of deep vein thrombosis after craniotomy
Objective To explore the risk factors of deep vein thrombosis(DVT)after craniotomy.Methods Data from 202 patients who rcceived craniotomy at the Department of Neurosurgery of Jiangsu Provincial People's Hospital between January 2019 and December 2022 were retrospectively analyzed.The patients were divided into two groups based on the occurrence of postoperative DVT.The control group(n= 160)had no DVT,while the case group(n= 42)had DVT.The independent risk factors for DVT after craniotomy were analyzed,and the predictive effect of DVT after craniotomy was analyzed using a logistic regression model.Results Among all the patients investigated,42 patients developed DVT,and the incidence of DVT was 20.79%.The result of univariate analysis showed that there were statistically significant differences in blood loss,absolute bed length after surgery,and the proportion of hypercoagulability between the two groups(P<0.05).The multi-factor model and independent influencing factors were used to predict the occurrence of DVT after craniotomy.The optimal cut-off values were 526.42 ml,9.78 d,0.50,27.15%,and the area under ROC curve was 0.763,0.859,0.730,0.948,respectively.The Yoden index was 62.41%,57.95%,46.04%and 82.47%,respectively.Conclusion Patients with craniotomy have a high risk of DVT after surgery.The establishment of the risk factor analyzer prediction model can better prevent and control this situation,help reduce the risk of patients and increase the success rate of surgery.

CraniotomyDeep vein thrombosisBody movementRisk predictionBlood loss

张婷、颜伟、吴娟、万志慧、赵琳

展开 >

210000 南京医科大学第一附属医院(江苏省人民医院)神经外科ICU

开颅手术 深静脉血栓 肢体运动 风险预测 失血量

江苏省"六大人才高峰"高层次人才项目(第十五批)

WSW-006

2024

中华保健医学杂志
中国人民解放军总后勤部卫生部保健局

中华保健医学杂志

CSTPCD
影响因子:0.477
ISSN:1674-3245
年,卷(期):2024.26(1)
  • 21