Application of SWIM thrombectomy technique in the treatment of acute craniocerebral great vessel occlusion
Objective To investigate the effect of Solitaire FR with intracranial support catheter for mechanical thrombectomy(SWIM)in the treatment of acute craniocerebral great vessel occlusion.Methods A total of 90 patients with acute craniocerebral great vessel occlusion admitted to our hospital from November 2020 to May 2022 were included in the study and divided into an observation group and a control group,with 45 cases in each group,by using random number table.The observation group received SWIM thrombectomy,while the control group underwent stent thrombectomy.Vascular recanalization was evaluated using thrombolysis in cerebral Infarction(TICI)treatment grading criteria after surgery.Preoperative and postoperative 1 week,we used National Institutes of Health Stroke Scale(NIHSS)to evaluate the neurological defects of the patients,and Barthel scale was used to assess the patients' self-care ability in daily life.The levels of neural function index[neuron-specific enolase(NSE),brain-derived neurotrophic factor(BDNF)and S100β protein(S100β)]in the two groups were compared before and 1 week after surgery.Prognosis was assessed by the modified Rankin scale(mRs)3 months after surgery,with the complications and mortality recorded in both groups.Results The proportion of patients with the vascular revascularization rate in the observation group were significantly higher than those in the control group(χ2=10.946,P<0.05).At 1 week after surgery,the NIHSS score in the observation group was lower than in the control group,and Barthel score in the observation group was higher than in the control group(t=3.567,5.594,P<0.05).Additionally,at 1 week after surgery,NSE and S100β levels in the observation group were lower than in the control group,and BDNF levels in the observation group were higher than in the control group(t=9.690,4.707,7.630,P<0.05).Complication rates were similar between the two groups(P>0.05).The mRs score of the observation group was lower than that of the control group 3 months after operation(P<0.05).There was no significant difference in the incidence of complications and mortality between the two groups(χ2= 0.549,0.714,P>0.05).Conclusion SWIM thrombectomy can better restore blood perfusion in patients with acute craniocerebral occlusion,improve nerve defects,improve their self-care ability,and improve patients' prognosis.
Acute craniocerebral great vessel occlusionMechanical thrombectomyIntracranial support catheterVascular recanalization
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