Effect of indentation of PCNL nephrostomy tube on postoperative bleeding and inflammation
Objective To investigate the effects of percutaneous nephrolithotripsy(PCNL)onpostoperative bleeding and inflammation.Methods A retrospective analysis was performed on the clinical data of 100 patients with renal calculus who received PCNL in our hospital from December 2017 to December 2021.The patients were divided into 2 groups according to whether the patients had indwelling nephrostomy tubes,with 50 cases in each group.The control group had indwelling nephrostomy tubes,while the study group did not.Calculus clearance rate,operation time and hospital stay were compared between the two groups.Meanwhile,postoperative bleeding,changes in inflammatory factors before and on the 1st day after surgery were compared between the two groups.Results The stone clearance rate and operation time of the control group and the study group were similar,and the difference was not statistically significant(P>0.05),while the hospital stay of the control group was longer than that of the study group(P<0.05).There was no significant difference in the incidence of postoperative bleeding(8.00%vs.6.00%)and the amount of postoperative bleeding[(221.47±42.58)ml vs.(215.68±39.74)]ml between the control group and the study group(P>0.05).On the first day after surgery,the levels of C-reactive protein(CRP),tumor necrosis factor-α(TNF-α)and interleukin-6(IL-6)in both groups were higher than those before surgery.The levels of CRP,TNF-α and IL-6 in the control group were(23.17±3.74)mg/L,(11.93±2.27)pg/L and(21.85±3.72)pg/L,respectively.It was significantly higher than that of the study group(20.85±3.6)mg/L,(10.75±2.11)pg/L,(19.68±3.55)pg/L(P<0.05).Conclusion In PCNL patients with or without renal fistulas,good stone removal rate can be achieved.But the renal fistulas may prolong the hospital stay,aggravate the postoperative inflammatory reaction and slow the recovery process down.
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