Risk factors of intracranial infection after transnasal resection of pituitary tumour
Objective To retrospectively analyze the risk factors of intracranial infection after transnasal resection of pituitary tumour.Methods From March 2021 to March 2023,119 patients with pituitary tumour who underwent transnasal resection in our hospital were retrospectively analyzed.The patients with intracranial infection after operation were included in the infection group,and those without intracranial infection were included in the non infection group.The clinical data and the levels of tissue related factors of pituitary tumour in the two groups were compared,and the risk factors of intracranial infection after pituitary tumour resection via nasal approach were analyzed by single factor and multifactorial logistic regression analysis.Results Among 119 cases of pituitary tumour resection via nasal approach,18 cases(15.13%,18/119)had postoperative intracranial infection.Single factor analysis showed that age≥60 years,operation time≥4 h,intraoperative bleeding≥120 ml,cerebrospinal fluid leakage,diabetes and growth hormone tumor were the influencing factors of intracranial infection in patients undergoing pituitary tumour resection via nasal approach(P<0.05).Multivariate logistic regression analysis showed that age≥60 years,operation time≥4 h,cerebrospinal fluid leakage and growth hormone tumor were independent risk factors for intracranial infection after transnasal pituitary tumour resection(P<0.05).Conclusion Age≥60 years,operation time≥4 hours,cerebrospinal fluid leakage and growth hormone tumor are independent risk factors for intracranial infection after transnasal resection of pituitary tumour.Clinical preventive measures should be taken actively to reduce the incidence of postoperative intracranial infection and improve the prognosis of patients.
Transnasal resection of pituitary tumourIntracranial infectionRisk factors
NETL
NSTL
万方数据
