首页|左心耳封堵术后行房颤电复律的有效性及安全性研究

左心耳封堵术后行房颤电复律的有效性及安全性研究

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目的 探讨左心耳封堵(LAAO)术后患者行房颤电复律治疗的有效性及安全性。方法 25 例左心耳封堵器植入后行电复律治疗的患者为电复律组,通过 1∶1匹配从同期 243 例未行电复律治疗的封堵器植入患者中选取 25 例纳入对照组。主要安全性观察指标为随访期间患者不良事件发生率,有效性观察指标为随访期间窦性心律维持率。结果 电复律组患者年龄 45~82 岁,电复律即刻成功率 84%,术后 6 个月随访时有 9 例(36%)依然维持窦律。电复律组有 2 例患者术后分别发生出血和短暂性脑缺血发作;对照组术后发生 3 例不良事件,包括 2 例卒中、1 例设备相关血栓。两组随访不良事件发生率差异无统计学意义(P>0。05)。结论 对于不适合行射频消融联合左心耳封堵"一站式"手术但存在转复意愿的房颤患者,单纯左心耳封堵术后接受电复律治疗是安全且有效的。
The feasibility and safety of electrical cardioversion of atrial fibrillation in patients with left atrial appendage occlusion
Objective The purpose of this study was to assess the feasibility and safety of electrical cardioversion(ECV)in patients with left atrial appendage occluder implantation.Methods Twenty-five patients with left atrial appendage occluder implantation were enrolled in the ECV group undergoing ECV.The control group undergoing LAAO alone was formed by 1∶1 matching from 243 patients with occluder implantation without ECV.We record the incidences of major adverse events during the follow-up as the safety observation index,and the maintenance rate of sinus rhythm during the follow-up as the feasibility observation index.Results In the ECV group,the patient age is between 45 and 82 years old,and cardioversion was immediately successful in 21(84%)patients.At the Six-month follow-up,9 patients(36%)maintained sinus rhythm.During the follow-up,two patients in ECV group experienced bleeding and transient ischemic attack,respectively.There were three adverse events in the control group,including two cases of stroke and one device-related thrombosis.There was no significant difference in the incidence of adverse events between the two groups.Conclusion For atrial fibrillation(AF)patients with alone LAAO who are not suitable for catheter ablation in combination with LAAO treatment,but have the intention of cardioversion,ECV is safe and effective.

Atrial fibrillationDirect current cardioversionLeft atrial appendage occlusionSinus rhythm

孟现赛、陈韬、王鑫焱、刘奥、沈娟、郭军

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100048 北京,解放军总医院第六医学中心心血管病医学部

心房颤动 电复律 左心耳封堵术 窦性心律

全军后勤科研计划面上项目

22BJZ41

2024

中华保健医学杂志
中国人民解放军总后勤部卫生部保健局

中华保健医学杂志

CSTPCD
影响因子:0.477
ISSN:1674-3245
年,卷(期):2024.26(2)
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