首页|心脏骤停患者呼气末二氧化碳分压与自主循环恢复关系的研究

心脏骤停患者呼气末二氧化碳分压与自主循环恢复关系的研究

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目的 探讨心脏骤停(CA)患者呼气末二氧化碳分压(PETCO2)与自主循环恢复(ROSC)的关系研究。方法 回顾性选取 2018 年 5 月~2023 年 5 月就诊于北京大学第三医院秦皇岛医院急诊科及重症医学科成人CA患者 107 例的数据。分析CA患者PETCO2 水平与ROSC的关系。结果 107 例CA患者经心肺复苏术(CPR)抢救治疗后,73 例患者自主循环恢复设为ROSC组,34 例患者复苏失败设为无ROSC组。ROSC组在 10、20 和 30 min时PETCO2 均高于无ROSC组,差异有统计学意义(t=29。457、56。934、51。801,P<0。05)。107 例CA患者中共有 67 例患者存活(存活组),40 例患者死亡(死亡组)。两组 0 min时PETCO2 差异无统计学意义(t=0。504,P=0。615);存活组在 10、20 和 30 min时PETCO2 均高于死亡组,差异有统计学意义(t=16。955、14。757、17。071,P<0。05);PETCO2、CA对 ROSC 造成影响时,标准化路径系数分别为 0。182、0。187、0。353,路径呈现出的 0。05 水平的显著性(Z=2。283、2。340、5。798,P<0。05)。结论 CA患者PETCO2 水平与ROSC的关系为正向影响关系,可以监测并预估患者CPR质量。
A study of the relationship between partial pressure of end-expiratory carbon dioxide and recovery of autonomic circulation in patients with cardiac arrest
Objective To investigate the study of the relationship between partial pressure of end-expiratory carbon dioxide(PETCO2)and recovery of autonomic circulation(ROSC)in patients with cardiac arrest(CA).Methods Data from 107 adult CA patients who attended the emergency department and department of critical care medicine of Qinhuangdao Hospital,Peking University Third Hospital from May 2018 to May 2023 were selected for retrospective study.The relationship between PETCO2 levels and ROSC in CA patients was analyzed.Results In 107 CA patients,after CPR resuscitation treatment,73 patients with recovery of autonomic circulation were set as ROSC group.34 patients with resuscitation failure were set as no ROSC group.There was no difference in the comparison of age,gender,CPR start time,CPR end time,ventilation mode,ECC mode,epinephrine dose,defibrillation times and other data between the two groups(P>0.05).PETCO2 was higher in the ROSC group than the no-ROSC group at 10 min,20 min and 30 min(P<0.05).Among 107 patients,67 patients survived and 40 patients died.There was no difference in PETCO2 at 0 min between the survival group and the death group(P>0.05),and PETCO2 in the survival group was higher than that in the death group at 10 min,20 min,and 30 min(P<0.05).The standardised path coefficients of PETCO2 and CA when they had an effect on ROSC were 0.182,0.187,and 0.353,respectively,which were>0.The paths showed a significance at the 0.05 level(Z=2.283,2.340,5.798,P<0.05),indicating a positive relationship of PETCO2,CA on ROSC.Conclusion The relationship between PETCO2 level and ROSC in CA patients is a positive influence relationship,which can monitor and predict the quality of CPR in patients.

Cardiac arrestPartial pressure of carbon dioxide at end-expirationRecovery of autonomic circulation

王晓蕾、王秋艳、于美军、陈静、曾君、李力平、吴双

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066000 秦皇岛,北京大学第三医院秦皇岛医院重症医学科

066000 秦皇岛,北京大学第三医院秦皇岛医院急诊科

心脏骤停 呼气末二氧化碳分压 自主循环恢复

秦皇岛科技计划

202301A083

2024

中华保健医学杂志
中国人民解放军总后勤部卫生部保健局

中华保健医学杂志

CSTPCD
影响因子:0.477
ISSN:1674-3245
年,卷(期):2024.26(2)
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