A study of the relationship between partial pressure of end-expiratory carbon dioxide and recovery of autonomic circulation in patients with cardiac arrest
Objective To investigate the study of the relationship between partial pressure of end-expiratory carbon dioxide(PETCO2)and recovery of autonomic circulation(ROSC)in patients with cardiac arrest(CA).Methods Data from 107 adult CA patients who attended the emergency department and department of critical care medicine of Qinhuangdao Hospital,Peking University Third Hospital from May 2018 to May 2023 were selected for retrospective study.The relationship between PETCO2 levels and ROSC in CA patients was analyzed.Results In 107 CA patients,after CPR resuscitation treatment,73 patients with recovery of autonomic circulation were set as ROSC group.34 patients with resuscitation failure were set as no ROSC group.There was no difference in the comparison of age,gender,CPR start time,CPR end time,ventilation mode,ECC mode,epinephrine dose,defibrillation times and other data between the two groups(P>0.05).PETCO2 was higher in the ROSC group than the no-ROSC group at 10 min,20 min and 30 min(P<0.05).Among 107 patients,67 patients survived and 40 patients died.There was no difference in PETCO2 at 0 min between the survival group and the death group(P>0.05),and PETCO2 in the survival group was higher than that in the death group at 10 min,20 min,and 30 min(P<0.05).The standardised path coefficients of PETCO2 and CA when they had an effect on ROSC were 0.182,0.187,and 0.353,respectively,which were>0.The paths showed a significance at the 0.05 level(Z=2.283,2.340,5.798,P<0.05),indicating a positive relationship of PETCO2,CA on ROSC.Conclusion The relationship between PETCO2 level and ROSC in CA patients is a positive influence relationship,which can monitor and predict the quality of CPR in patients.
Cardiac arrestPartial pressure of carbon dioxide at end-expirationRecovery of autonomic circulation