Bland-Altman consistency evaluation of two methods in preoperative evaluation of left atrial appendage occlusion in patients with atrial fibrillation
Objective To explore the consistency of left atrial appendage(LAA)measurement parameters between cardiac computer tomography angiography(CCTA)imaging-based automatic segmentation and manual measurement method.Methods Clinical and imaging data of non-valvular atrial fibrillation patients who underwent CCTA at the department of cardiovascular medicine,General Hospital of the PLA from December 1,2016,to March 31,2020,were collected retrospectively.Using manual measurement by professional physicians as the gold standard,Bland-Altman statistical method were used to analyze the consistency of LAA orifice plane circumference,longest diameter,shortest diameter,LAA volume,and the angle between the orifice plane and the axial,sagittal,and coronal planes,respectively,measured automatically using Anythinkβ software.Results The ICC values for the consistency evaluation of the perimeter,longest diameter,and shortest diameter of the left atrial appendage between automatic and manual measurements were 0.93,0.854,and 0.935,respectively(P<0.01).Bland-Altman analysis showed that the number of points where the difference between the automatic measurement values of the LAA orifice plane circumference,longest diameter,shortest diameter,LAA volume,and the angle between the orifice plane and the axial,sagittal,and coronal planes and the manual measurement values exceeded the 95%limits of agreement was less than 10%.Conclusion The CCTA-based automatic segmentation measurement method of the LAA efficiently identifies LAA morphology and measure related parameters with high accuracy and reproducibility.It can be used as a measurement tool for preoperative evaluation of LAAO.