Independent risk factors for bacterial infection in patients with chronic renal failure undergoing CRRT
Objective To investigate independent risk factors for bacterial infection in patients with chronic renal failure undergoing continuous renal replacement therapy(CRRT).Methods Clinical data from 1 000 patients with chronic renal failure who underwent CRRT in the hospital from December 2019 to December 2022 were retrospectively analyzed.The occurrence of bacterial infections was recorded,and the distribution of pathogenic bacteria was analyzed.Patients with bacterial infections comprised the observation group,while those without formed the control group.Baseline chracteristics between the two groups were comparatively analyzed.Binary logistic regression analysis was conducted to identify the independent risk factors for bacterial infection in patients with chronic renal failure undergoing CRRT.Results A total of 267 patients developed bacterial infections(observation group),with an incidence rate of 26.70%.There were statistically significant differences between the observation group and the control group in terms of age,treatment time,body mass index(BMI),diabetes,diabetic nephropathy,heart failure,indwelling venous catheter,hemoglobin(Hb)and serum albumin(χ2=8.123,5.463,8.631,5.043,8.898,8.052,4.861,8.658,4.803,P<0.05).Multivariate logistic regression analysis result showed that age≥65 years,treatment time≥1 year,BMI<20 kg/m2,diabetes,heart failure,indwelling venous catheter,diabetic nephropathy,Hb level<70 g/L and serum albumin level<30 g/L were independent risk factors for bacterial infection in patients with chronic renal failure undergoing CRRT(P<0.05).Conclusion Age,treatment time,BMI,diabetes,heart failure,indwelling venous catheter,diabetic nephropathy,Hb and serum albumin are influencing factors of bacterial infection in patients with chronic renal failure undergoing CRRT.Clinically,intervention measures should be taken against the above risk factors to prevent bacterial infection.
NETL
NSTL
万方数据
