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急性非静脉曲张性上消化道出血患者禁食持续时间探讨

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目的 观察急性非静脉曲张性上消化道出血(ANVUGIB)患者止血后早期经口进食对再出血等临床转归的影响。方法 选取南京医科大学附属淮安第一医院 2020 年 2 月~2023 年 8 月期间 120 例因ANVUGIB住院患者,随机数表法分为早期进食组和常规禁食组,各 60 例。早期进食组内镜检查止血治疗后出血明显好转,无频繁呕吐,血流动力学稳定 12 h内经口进食。常规禁食组止血后禁食水 72 h,给予静脉营养。比较两组患者住院时间、再次出血率及院内死亡率。比较两组患者治疗前、治疗 3 d后血钾(K+)、血钠(Na+)、血红蛋白(Hb)、白蛋白(Alb)水平。结果 两组年龄、性别、Forrest分级、出血部位及是否输血比较,差异均无统计学意义(P>0。05)。入组时及止血后 3 d两组间Hb、Alb、K+、Na+比较,差异均无统计学意义(P>0。05)。早期进食组平均住院时间(4。92±2。07)d,低于常规禁食组的(6。15±2。83)d,组间差异有统计学意义(t=2。717,P=0。008)。两组再出血率和院内死亡率差异均无统计学意义(P>0。05)。结论 对于急性非静脉曲张性上消化道出血患者内镜检查止血治疗后 12 h内经口进食缩短了住院时间,且未提高再发出血风险和死亡率。
Discussion on the duration of fasting in patients with acute non varicose upper gastrointestinal bleeding
Objective To observe the effect of early oral feeding after hemostasis on clinical outcomes such as rebleeding in patients with acute non variceal upper gastrointestinal bleeding(ANVUGIB).Methods A total of 120 hospitalized patients with ANVUGIB from February 2020 to August 2023 were randomly divided into two groups.The early feeding group(n=60)resumed oral intake within 12 hours after endoscopic examination and hemostasis treatment,without experiencing frequent vomiting and maintaining stable hemodynamics.The conventional fasting group(n=60)fasted with water for 72 hours after hemostasis and received intravenous nutrition.Hospitalization time,rebleeding rate,and hospital mortality rate were compared between the two groups.Compare the levels of blood potassium(K+),blood sodium(Na+),hemoglobin(Hb),and albumin(Alb)between the two groups before and after treatment for 3 days.Results There was no statistically significant difference in age,gender,Forrest grading,bleeding site,and whether blood transfusion was performed between the two groups(P>0.05).There was no statistically significant difference in Hb,Alb,K+,Na+between the two groups before and 3 days after treatment(P>0.05).The average hospitalization time of the early eating group was(4.92±2.07)days,which was lower than the(6.15±2.83)days of the conventional fasting group.There was a statistically significant difference between the groups(t=2.717,P=0.008).There was no statistically significant difference in rebleeding rate and hospital mortality rate between the two groups(P>0.05).Conclusion For patients with acute non-variceal upper gastrointestinal bleeding,oral feeding within 12 hours after endoscopic examination and hemostasis treatment shortenes hospitalization time without increasing the risk of recurrent bleeding and mortality.

Acute non variceal upper gastrointestinal bleedingOral feedingFastingrebleeding

刘业红、申曌

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223300 淮安,南京医科大学附属淮安第一医院消化科

急性非静脉曲张性上消化道出血 经口进食 禁食 再出血

江苏省科技计划社会发展面上项目

BE2019636

2024

中华保健医学杂志
中国人民解放军总后勤部卫生部保健局

中华保健医学杂志

CSTPCD
影响因子:0.477
ISSN:1674-3245
年,卷(期):2024.26(3)