首页|超声引导下微创旋切术和小切口乳腺结节切除术对乳腺良性肿瘤疗效及对疼痛程度、免疫功能及应激程度影响

超声引导下微创旋切术和小切口乳腺结节切除术对乳腺良性肿瘤疗效及对疼痛程度、免疫功能及应激程度影响

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目的 探究超声引导下微创旋切术和小切口乳腺结节切除术对乳腺良性肿瘤疗效及对疼痛程度、免疫功能及应激程度影响。方法 回顾性选取 2020 年 2 月~2023 年5 月在庐江县中医院接受治疗的92 例初诊乳腺良性肿瘤患者。根据不同的手术方式将患者分为微创旋切组和结节切除组,每组各46 例。微创旋切组患者接受超声引导的微创旋切术治疗,结节切除组接受小切口乳腺结节切除术治疗。术后观察比较两组患者手术指标、疼痛程度、应激反应、免疫功能、并发症及乳房美观度。结果 微创旋切组术中出血量、视觉模拟量表(visual analog scale,VAS)评分均低于结节切除组,手术时间短于结节切除组,差异有统计学意义(t=12。960、5。072、4。099,P<0。05)。术后,微创旋切组肾上腺素(epinephrine,E)、去甲肾上腺素(norepinephrine,NE)、皮质醇(cortisol,Cor)水平均低于结节切除组,差异有统计学意义(t=4。209、2。763、31。856,P<0。05)。微创旋切组淋巴细胞亚群 CD4+、CD3+、CD4+/CD8+均高于结节切除组,差异有统计学意义(t=10。329、6。639、18。507,P<0。05)。微创旋切组并发症总发生率低于结节切除组,乳房美观优良率高于结节切除组,差异均有统计学意义(χ2=7。256、9。583,P<0。05)。结论 采用超声引导下微创旋切术治疗乳腺良性肿瘤患者,创伤小、并发症少且疼痛轻微,有利于减轻机体应激反应,对患者免疫功能影响较小,利于提高乳房美观度,是一种安全、有效的治疗术式。
Ultrasound-guided minimally invasive rotary resection and small incision breast nodule resection for benign breast tumors and their effects on pain degree,immune function and stress degree
Objective To explore the effects of ultrasound-guided minimally invasive rotary resection and small incision breast nodule resection on benign breast tumors,focusing on their impact on pain levels,immune function and stress responses.Methods A retrospective study was conducted on 92 patients newly diagnosed with benign breast tumors at Lujiang County Hospital of TCM from February 2020 to May 2023.According to different surgical method,the patients were divided into minimally invasive rotary resection group and nodular resection group,with 46 patients in each group.Patients in the minimally invasive rotary cutting group were treated with ultrasound-guided minimally invasive rotary cutting,and patients in the nodule resection group were treated with small incision breast nodule resection.The surgical indexes,pain degree,stress response,immune function,complications,and breast aesthetics were observed and compared between the two groups after operation.Results Intraoperative blood loss and visual analog scale(VAS)score were significantly lower in the minimally invasive rotary resection group compared to the nodular resection group,and the operation time was shorter in the former(t=12.960,5.072,4.099,P<0.05).The levels of epinephrine(E),norepinephrine(NE)and cortisol(Cor)in the minimally invasive rotary resection group were lower than those in the nodular resection group(t=4.209,2.763,31.856,P<0.05).The lymphocyte subsets CD4+,CD3+and CD4+/CD8+were higher than those in the nodular resection group(t=10.329,6.639,18.507,P<0.05).And the total incidence of complications was lower than that in the nodular resection group.The excellent and good rate of breast aesthetics was higher than that of the nodule resection group,and the differences were statistically significant(χ2=7.256,9.583,P<0.05).Conclusion Ultrasound-guided minimally invasive rotary resection proves to be a safe and effective treatment for benign breast tumors.It offers reduced trauma,fewer complications and milder pain,thereby minimizing the body's stress response and preserving immune function.Moreover,it contributes to improving the beauty of the breast.

Minimally invasive rotary cuttingSmall incision breast nodule resectionBenign breast tumorThe degree of painImmune functionStress response

左从奎、毕迎春、姚琼

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231500 合肥,庐江县中医院普外科

231500 合肥,庐江县中医院骨伤科

微创旋切术 小切口乳腺结节切除术 乳腺良性肿瘤 疼痛程度 免疫功能 应激反应

安徽省重点研发计划

202106a05031156

2024

中华保健医学杂志
中国人民解放军总后勤部卫生部保健局

中华保健医学杂志

CSTPCD
影响因子:0.477
ISSN:1674-3245
年,卷(期):2024.26(3)