Comparative analysis of rehabilitation effect of staged cardiac rehabilitation training and traditional rehabilitation training in patients with hypertension complicated with acute myocardial infarction
Objective To explore the application effect of sacubitril valsartan combined with staged cardiac rehabilitation training in the rehabilitation of hypertension complicated with acute myocardial infarction(AMI).Methods A total of 120 patients with hypertension and AMI diagnosed and treated in Wuxi Xishan People's Hospital from January 2020 to May 2023 were prospectively selected as the research objects.The patients were divided into stage rehabilitation group and traditional rehabilitation group by random number table method,with 60 patients in each group.The patients in the traditional rehabilitation group were given sacubitril valsartan and routine cardiac rehabilitation training intervention,and the patients in the stage rehabilitation group were given sacubitril valsartan combined with stage cardiac rehabilitation training intervention.Blood pressure,left ventricular end-systolic dimension(LVESD),heart rate,left ventricular end-diastolic dimension(LVEDD),left ventricular ejection fraction(LVEF),creatinine(Cr),serum potassium,creatine kinase isoenzyme-MB(CK-MB),N-terminal pro-brain natriuretic peptide(NT-proBNP),lactate dehydrogenase(LDH),6 minute walking distance(6MWD),common adverse reactions and major adverse cardiac events were observed and compared between the two groups before and after intervention.Results There was no difference in systolic blood pressure,diastolic blood pressure,heart rate and adverse reaction rate between the two groups before and after intervention(P＞0.05).After intervention,the levels of NT-proBNP,Cr,serum potassium,CK-MB,LVESD and LVEDD in the stage rehabilitation group were significantly lower than those in the traditional rehabilitation group,the levels of LVEF,6MWD and LDH were significantly higher than those in the traditional rehabilitation group(t=5.087,12.334,3.102,4.603,4.130,3.500,5.488,6.245,4.275,P＜0.05).There was no significant difference in the total incidence of complications between the two groups after intervention(P＞0.05).The incidence of major adverse cardiac events(MACE)in the staged rehabilitation group was lower than that in the traditional rehabilitation group during the 6-month follow-up period(t=5.566,P=0.018).Conclusion The application effect of Sacubitril Valsartan combined with staged cardiac rehabilitation training in the rehabilitation of hypertension complicated with AMI is good,which can effectively promote the recovery of cardiac function and has high safety.
万方数据
维普
