The therapeutic effect of Shentong Zhuyu Decoction on reducing acute skeletal muscle injury pain and its impact on serum inflammatory factors
Objective To explore body pain by stasis soup curative effect and mechanism of acute skeletal muscle injury.Methods Eighty-two individuals suffering from acute skeletal muscle injuries were randomly assigned to either a traditional Chinese medicine cohort or a Western medicine cohort.The TCM group received Shentongzhuyu Decoction,and the Western medicine group received diclofenac sodium dual-release enteric-coated capsules.Observe two groups of patients with impaired skeletal muscle pain score and serum inflammatory factors change.Results Following a week of treatment with traditional Chinese medicine,individuals in this cohort experienced a reduced pain index of(0.61±0.80),notably less than the(1.46±1.43)recorded in the group receiving Western medical treatments,indicating a considerable statistical variance between the two factions(t=-3.337,P<0.05).Moreover,in the cohort treated with traditional Chinese medicine,the levels of TNF-α,IL-6,CRP,and IL-8 were observed at 4.82±2.24 pg/ml,2.09±1.52pg/ml,0.34±0.20mg/dL and 26.13±13.23pg/ml,respectively.Compared with the western medicine group 9.10±3.47pg/ml,3.24±2.11 pg/ml,0.49±0.26mg/dL,36.72±16.68pg/ml,there were significant statistical differences(t=-6.650,-2.846,-3.125,-3.184,P<0.05).Conclusion The treatment of acute skeletal muscle injury with Shen Tong Zhu Yu Decoction can significantly reduce the degree of pain,and its partial mechanism of action is to inhibit the release of inflammatory factors,which is worth promoting and applying in clinical practice.
Shentongzhuyu DecoctionAcute injury of skeletal musclePainscoreInflammatory factor