Impact of modified Yiqi tongmai decoction on lipid metabolism and myocardial enzyme profiles in patients with acute myocardial infarction post-percutaneous coronary intervention
Objective This study aimed to evaluate the impact of the modified Yiqi Tongmai Decoction on lipid metabolism and myocardial enzyme profiles in patients who underwent percutaneous coronary intervention(PCI)following acute myocardial infarction(AMI).Methods A cohort of 80 AMI patients post-PCI was randomly assigned to either the control group(n=39)or the treatment group(n=41).The control group received standard Western medical treatment,while the treatment group received the modified Yiqi Tongmai Decoction in addition to the standard treatment for a period of 8 weeks.The Traditional Chinese Medicine(TCM)syndrome scores,lipid metabolism,myocardial enzymes,and safety were assessed for both groups.Results After 8 weeks of treatment,the TCM syndrome scores for chest pain,chest distress,palpitations,shortness of breath,fatigue,sweating,and dark complexion in the treatment group were significantly lower than those in the control group(P<0.05).The treatment group also exhibited lower levels of cholesterol,triglycerides,lipoprotein(a),and low-density lipoprotein cholesterol,and higher levels of high-density lipoprotein cholesterol compared to the control group(P<0.05).Additionally,the treatment group had reduced levels of creatine kinase,lactate dehydrogenase,aspartate transaminase,and creatine kinase isozyme compared to the control group(P<0.05).The total effective rate in the treatment group was significantly higher than that in the control group(P<0.05).Conclusion The combination of standard Western medical treatment with the modified Yiqi Tongmai Decoction is effective in improving outcomes for AMI patients post-PCI.It significantly reduces TCM syndrome scores,lipid levels,and myocardial damage,and demonstrates a favorable safety profile.
万方数据
维普
