首页|普拉克索药物联合动静态平衡训练对老年帕金森患者运动功能、生活质量及自我负担的影响

普拉克索药物联合动静态平衡训练对老年帕金森患者运动功能、生活质量及自我负担的影响

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目的 分析普拉克索药物联合动静态平衡训练对老年帕金森患者运动功能、生活质量及自我负担的影响。方法 回顾性选取 2021 年 8 月~2023 年8 月淮安市第一人民医院收治的138 例老年帕金森患者,根据治疗方案的不同分为药物组(n=65)和联合组(n=73)。药物组采用普拉克索和常规的康复训练进行治疗,联合组在药物组的基础上联合动静态平衡训练进行治疗。比较两组患者帕金森相关症状评分情况、运动功能、平衡能力、生活质量、自我负担及不良反应发生情况。结果 治疗后,联合组患者的统一帕金森病评定量表第一部分(UPDRSⅠ)、评分和简易智力状态检查量表(MMSE)评分、统一帕金森病评定量表第三部分(UPDRSⅢ)评分、冻结步态问卷(FOGQ)评分、前后平衡指数、左右平衡指数、总体平衡指数均低于药物组患者(t=5。675、17。927、6。076、3。314、4。861、5。594、8。158,P<0。05);生活质量(物质生活状态、躯体功能、社会功能、心理功能)评分均高于药物组患者(t=3。937、8。192、7。073、12。800,P<0。05);自我负担情况(身体负担、情感负担、经济负担)评分及总分均低于药物组患者,差异均有统计学意义(t=2。523、3。830、4。129、5。640,P<0。05);不良反应总发生率低于药物组,差异有统计学意义(χ2=4。337,P=0。037)。结论 采取普拉克索联合动静态平衡训练进行治疗可以明显改善老年帕金森患者的神经系统症状,促进运动功能的恢复,增强平衡能力,提高生活质量,减轻自我负担,减少不良反应。
Effects of dynamic and static balance training combined with pramipexole on motor function,quality of life and self-burden in elderly patients with Parkinson's disease
Objective To analyze the effect of dynamic and static balance training combined with pramipexole on movement function,health-related quality of life and self-burden in elderly patients with Parkinson's disease.Methods A total of 138 elderly patients with Parkinson's disease admitted to Huai'an First People's Hospital from August 2021 to August 2023 were retrospectively selected as the research objects.According to the treatment plan,they were divided into drug group(n=65)and combined group(n=73).The drug group was treated with pramipexole and routine rehabilitation training,and the combined group was treated with dynamic and static balance training on the basis of the drug group.The scores of related symptoms,motor function,balance ability,quality of life,self-burden and adverse reactions were compared between the two groups.Results After treatment,the UPDRSⅠ,MMSE score,UPDRSⅢ score,FOGQ score,anterior-posterior balance index,left-right balance index,overall balance index,body burden,emotional burden,economic burden and total score of the combined group were lower than those of the drug group(t=5.675,17.927,6.076,3.314,4.861,5.594,8.158,2.523,3.830,4.129,5.640,P<0.05).The quality of life in the combined group was higher than that in the drug group(t=3.937,8.192,7.073,12.800,P<0.05).The total adverse rate of the combined group(8.22%)was significantly lower than that of the drug group(20.00%)(χ2=4.337,P<0.05).Conclusion Dynamic and static balance training combined with pramipexole can significantly improve the neurological symptoms of mental and cognitive impairment in elderly patients with Parkinson's disease,promote the recovery of motor function,enhance balance ability,improve quality of life and reduce self-burden level.

Dynamic and static balance trainingPramipexoleElderly Parkinson's disease

蒋娟、陈萍、孙振杰

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223300 南京医科大学附属淮安第一医院神经内科

动静态平衡训练 普拉克索 老年帕金森病

江苏省卫生健康委员会科研项目

M2022082

2024

中华保健医学杂志
中国人民解放军总后勤部卫生部保健局

中华保健医学杂志

CSTPCD
影响因子:0.477
ISSN:1674-3245
年,卷(期):2024.26(5)