首页|1562例绝经后女性人群骨密度与握力相关性研究

1562例绝经后女性人群骨密度与握力相关性研究

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目的 分析 1562 例绝经后女性人群骨密度与握力之间的相关性。方法 收集 2022 年 5 月～2023 年 8 月于解放军总医院第一医学中心放射诊断科行骨密度检查与握力测试的 1562 例绝经后女性人群的骨密度检查结果与握力测试数据。按照年龄分成 3 组，分别是A组(<60 岁，n=663)、B组(60～74 岁，n=749)、C组(≥75 岁，n=150)。对 1562 例绝经后女性进行腰椎与股骨近端骨密度检查及优势侧手握力测试。比较 3 组的骨密度和握力，分析骨密度与握力之间的相关性。结果 腰椎骨密度T≤-2。5 SD的患者 501 例(32。07%);股骨颈骨密度T≤-2。5 SD的患者383 例(24。52%);髋部骨密度T≤-2。5 SD的患者 186 例(11。91%)。A组患者的握力为(22。35±4。64)kg，B组患者的握力为(19。81±4。94)kg，C组患者的握力为(16。57±4。27)kg。握力、骨密度均随着年龄的增长逐渐降低(P<0。05)。共 125 例患者既往发生过骨折(8。00%)，其中A组 28 例(4。22%)，B组 66 例(8。81%)，C组 31 例(20。67%)。随着患者年龄的增长，骨折的发生率升高(P<0。05)。相关性分析结果显示，绝经后女性人群的握力与股骨颈、髋部、腰椎骨的骨密度均呈正相关(r=0。936、0。938、0。935，P<0。05);握力、股骨颈骨密度、髋部骨密度、腰椎骨密度均与年龄呈负相关(r=-0。928、-0。967、-0。971、-0。970，P<0。05)。握力与腰椎、股骨颈、髋部骨密度均呈正相关(r=0。935、0。936、0。938，P<0。05);握力、股骨颈骨密度、髋部骨密度、腰椎骨密度均与BMI呈正相关(r=0。932、0。982、0。985、0。982，P<0。05)。结论 绝经后女性人群的握力与骨密度相互依存，相互影响，呈正相关;握力、骨密度与绝经后女性人群的年龄呈负相关。
The correlation between bone mineral density and grip strength in 1562 postmenopausal women patients
Objective To analyze the correlation between bone mineral density(BMD)and grip strength in a cohort of 1,562 postmenopausal women.Methods We collected BMD examination results and grip strength test data from 1,562 postmenopausal women who underwent these tests at the Department of Radiology,First Medical Center of Chinese PLA General Hospital,between May 2022 and August 2023.Patients were divided into three age groups:<60 years(n=663),60-74 years(n=749),and≥75 years(n=150).BMD of the lumbar spine and proximal femur,as well as dominant-side grip strength,were assessed.The BMD and grip strength of the three groups were compared,and the correlation between BMD and grip strength was analyzed.Results Among the patients,501(32.07%)had lumbar spine BMD T-scores≤-2.5;383(24.52%)had femoral neck BMD T-scores≤-2.5;and 186(11.91%)had hip BMD T-scores≤-2.5.Grip strength was(22.35±4.64)kg for the<60 years group,(19.81±4.94)kg for the 60-74 years group,and(16.57±4.27)kg for the≥75 years group.Both grip strength and BMD decreased with increasing age(P<0.05).A total of 125 patients(8.00%)had a history of fractures,with 28(4.22%)in the<60 years group,66(8.81%)in the 60-74 years group,and 31(20.67%)in the≥75 years group.The incidence of fractures increased with age(P<0.05).Correlation analysis showed that grip strength in postmenopausal women was positively correlated with femoral neck,hip,and lumbar spine BMD(r=0.145,0.139,0.107,respectively;P<0.05).Grip strength,femoral neck BMD,hip BMD,and lumbar spine BMD were all negatively correlated with age(r=0.230,-0.395,-0.378,-0.259,respectively;P<0.05).Grip strength was positively correlated with lumbar spine,femoral neck,and hip BMD(r=0.935,0.936,0.938,respectively;P<0.05).Grip strength,femoral neck BMD,hip BMD,and lumbar spine BMD were all positively correlated with BMI(r=0.032,0.265,0.321,0.283,respectively;P<0.05).Conclusion Grip strength and BMD are interdependent and positively correlated in postmenopausal women,while both are negatively correlated with age.

Bone mineral densityGrip strengthPostmenopausalPositive correlationNegative correlation

高登发、张晓晶、齐叶青、李萌、官剑武、贾红

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100853 北京,解放军总医院第一医学中心放射诊断科

北大医疗怡健殿诊所有限公司

骨密度 握力 绝经后 正相关 负相关

2024

10.3969∕j.issn.1674-3245.2024.05.029

中华保健医学杂志
中国人民解放军总后勤部卫生部保健局

中华保健医学杂志

CSTPCD
影响因子：0.477
ISSN：1674-3245
年,卷(期)：2024.26(5)