Effects of moderate-intensity resistance exercise on gestational weight gain and cardiometabolic profile in pregnant women with gestational diabetes mellitus
Objective To investigate the effects of moderate-intensity resistance exercise on gestational diabetes mellitus(GDM),gestational weight gain(GWG),and cardiometabolic profiles.Methods Taking 111 GDM patients who received prenatal follow-up in the Department of Endocrinology and High-risk Obstetrics of a tertiary general hospital from January 2020 to March 2022 as the study subjects,they were divided into observation group(n=55)and control group(n=56)according to the randomization method,with the observation group undergoing resistance exercise and the control group undergoing aerobic exercise.To study the effects of exercise patterns on GWG and cardiometabolic profiles.Results After the intervention,the average fasting blood glucose and 2h postprandial blood glucose levels in the observation group were lower than those in the control group,the difference was statistically significant(t=3.420,3.988,P<0.001).The proportion of macrosomia in control group(51.85%)was significantly higher than that in observation group(27.78%)(χ2=6.530,P=0.011).The body weight of the observation group before delivery,GWG significantly lower than the control group(P<0.05).In the observation group,systolic blood pressure before delivery,hemoglobin a1c(HbAlc),fasting insulin,Insulin resistance index(HOMA-IR),C-peptide were significantly lower than those in the control group(Z=-2.486、-2.205、-2.538、-2.755、-2.843,P<0.05).By partial correlation coefficient analysis,GWG and pre-delivery cardiometabolic spectrum,including systolic blood pressure,CRP,HbAlc,HOMA-IR,C-peptide(r=0.153,0.157,0.172,0.267,0.247,P<0.001)were positively correlated with serum HMW adiponectin level(r=-0.141,P=0.047).Conclusion Moderate-intensity resistance exercise improves glycaemic control,insulin use,gestational weight gain,and cardiovascular risk in people with GDM,and moderate-intensity resistance exercise is safe and feasible for pregnant women with GDM.
万方数据
维普
