Twelve Cases of Epilepsy Induced by Imipenemcilastatin:Literature Analysis
Objective To analyze the risk factors for epilepsy induced by imipenem cilastatin and to provide reference for safe and rational drug use.Methods The case reports of epilepsy induced by imipenem cilastatin were collected from such databases as CNKI and Wanfang before being analyzed.Results Twelve case reports of epilepsy induced by imipenem cilastatin were collected,involving 8 males and 4 females with an average age of(58.33±25.34).Seizure occurred as early as 6 hours after medication,and the frequency of seizure was up to 5 times.After drug withdrawal or symptomatic treatment,all the patients were in better condition.Conclusion Epilepsy can be induced by imipenem cilastatin,which deserves much attention in clinic.Those at high risk should receive better pharmaceutical care to ensure the safety of medication.
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