Research Progress in Pharmacological Action and Drug Combination of Simiaofang in the Treatment of Gout
Simiaofang is composed of Phellodendri Chinensis Cortex,atractylodes rhizoma,Coicis Semen and Achyranthis Bidentatae Radix,The four medicines work together to clear heat and remove dampness.It is mainly used to treat arthralgia such as swelling of feet and knees,pain of muscles and bones caused by dampness and heat.In this paper,the literature on the clinical treatment of gout with Simiaofang published between 2018 and 2023 was retrieved from CNKI,Wanfang,VIP,PubMed and Embase before being analyzed.The results showed that the combination of Simiaofang and chemical drugs(allopurinol,febuxostat,benzbromarone,colchicine,non-steroidal anti-inflammatory drugs)for the treat-ment of gout could reduce the level of serum uric acid,relieve joint swelling and pain,and contribute to the recovery of joint function.The research progress in applications of Simiaofang was summarized in terms of the curative effect,total effective rate and adverse reactions so as to provide reference for the clinical use and research of Simiaofang.
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