Objective To provide data for strengthening drug monitoring and early-warning and for improving rational clinical use of drugs by analyzing the current usage of drugs under state key surveil-lance.Methods The characteristics of drug consumers,defined daily dose(DDS),usage,comments on prescriptions and adverse drug reactions recorded in the recuperation system and outpatient system were analyzed based on the catalogues of drugs under state key surveillance.Results Fewer types of drugs under national key surveillance were used in recuperation institutions,and proton-pump inhibitor drugs were the most frequently used.There was significant difference in age and gender between users of ginkgo biloba extract tablets and those of betahistine mesylate tablets.Medications without indications,drug interactions and inappropriate dosage were dominating practices of irrational drug use.Most of the adverse drug reac-tions were reported by pharmacists rather by doctors and nurses.Conclusion The quality control circle management method based on plan,do,check,action(PDCA)will be applied to opt for a model of drug monitoring and early-warning suited to recuperation institutions in order to facilitate rational use of drugs during the switch to rehabilitation.
关键词
国家重点监控药品/用药频度/处方点评/药品不良反应
Key words
drugs under state key surveillance/defined daily doses/comments on prescriptions/adverse drug reactions