Rationality of Use of Antibiotics in Inpatients with COVID-19
Objective To investigate the usage of antibiotics in inpatients infected with COVID-19 and analyze the rationality so as to provide references for rational use of antibiotics.Methods The clinical data of COVID-19 patients in a hospital was collected,and the usage of antibiotics,infection-related indica-tors and results of etiological examination were statistically analyzed.The rationality of antimicrobial use was determined.Results A total of 170 patients were included,with 111 males(65.29％)and 59 females(34.71％).The average age was(73.56±14.18)years.Among these patients,149(87.65％)were treated with antibiotics.According to the results of laboratory examination,there were 74(49.66％)cases with elevated white blood cells,113(75.84％)with elevated C-reactive protein,22(14.70％)with procalcitonin levels above 0.5 ng·ml-1 and 21(16.8％)cases who were positive for microbial culture.The drug with the highest defend daily doses was piperacillin sodium and tazobactam sodium injection,followed by moxi-floxacin hydrochloride and sodium chloride injection.Irrational use of antibiotics was found in 22(13.42％)cases,involving inappropriate dosage(8.72％)and insufficient indications for use(3.36％).Conclusion The usage of antibiotics in COVID-19 patients is high.There exists irrational use of antibiotics in some patients.Clinicians should have an intimate knowledge of the indications of antibiotics use,strengthen etiological monitoring,and avoid haphazard or inappropriate use of antibiotics.
万方数据
维普
