解放军药学学报2024,Vol.37Issue(4) :398-402.DOI:10.3969/j.issn.1008-9926.2024.04.022

龙胆炮制的历史沿革及研究进展

Evolution of Gentian Processing and Research Progress

张勇帅 闫佳驹 刘丽娜 李慧勇 曹欢 笔雪艳
解放军药学学报2024,Vol.37Issue(4) :398-402.DOI:10.3969/j.issn.1008-9926.2024.04.022

龙胆炮制的历史沿革及研究进展

Evolution of Gentian Processing and Research Progress

张勇帅 1闫佳驹 2刘丽娜 3李慧勇 2曹欢 2笔雪艳2
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作者信息

  • 1. 150036 黑龙江哈尔滨,黑龙江省中医药科学院;150088 黑龙江哈尔滨,黑龙江省药品检验研究院
  • 2. 150088 黑龙江哈尔滨,黑龙江省药品检验研究院
  • 3. 150036 黑龙江哈尔滨,黑龙江省中医药科学院
  • 折叠

摘要

中药龙胆有悠久的药用历史具有清热燥湿、泻肝胆火等功效.古代龙胆的炮制方法有酒炙、蜜炒等,其主要目的在于缓和龙胆的苦寒之性,其中酒炙法沿用历史为悠久.现代龙胆的炮制方法以酒炙法为主,其目的在于缓和龙胆的苦寒之性,同时增加药材中龙胆苦苷等成分的溶出.本文系统归纳了古代典籍和现代各省(自治区、直辖市)《中药饮片炮制规范》中关于龙胆的炮制方法,归纳现有文献中龙胆炮制前后化学成分和药理作用的变化,并以此为依据分析古今龙胆炮制变化的原因,为后续龙胆的炮制方法及龙胆制品开发提供参考.

Abstract

The traditional Chinese medicine Radix gentianae has the effect of clearing heat and dampness,purging liver and gallbladder fire,and has a long history of medicinal use.The processing methods of Radix gentianae included alcohol or honey stir-fry in ancient times,which was intended to ease the bitter and cold properties of Radix gentianae.Among them,the alcohol stir-fry method has been the most widely used.By this means,the dissolution of gentiopicroside and other chemical components in the medicinal materials can be increased.This paper summarized the processing methods of Radix gentianae in ancient books and the processing standards for Chinese medicine decoction pieces in each province,and traced the changes of chemical constituents and pharmacological effects of Radix gentianae before and after processing.On this basis,the reasons for the changes of Radix gentianae processing in ancient and modern times were analyzed in order to provide a reference for subsequent development of Radix gentianae.

关键词

龙胆/炮制方法

Key words

Radix gentianae/processing method

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基金项目

国家药品监督管理局中药质量研究与评价重点实验室开放课题(NIFDC-7CU2023-0202-015)

出版年

2024
解放军药学学报
中国人民解放军总后勤部卫生部 药品仪器检验所

解放军药学学报

CSTPCD
影响因子:0.529
ISSN:1008-9926
参考文献量47
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