Efficacy and Safety of Piyanling Liniment in the Treatment of Chronic Eczema
Objective To investigate the clinical efficacy and safety of Piyanling liniment in the treatment of chronic eczema.Methods A total of 98 patients with chronic eczema were randomly divided into two groups.The Piyanling liniment group(n=49)was treated with Piyanling liniment while the Halcinon-ide solution group(n=49)was given Halcinonide solution.Both groups applied the respective treatment twice daily,at a dosage of 0.5 ml·cm-2 each time.Clinical symptoms,including the skin lesion size,skin lesion degree,pruritus degree,and pigmentation degree,were assessed before treatment and after 4,7,10,and 14 days of treatment.Additionally,the clinical efficacy and incidence of adverse drug reactions were compared between the two groups.Results Both groups exhibited progressive improvements in the skin lesion size,skin lesion degree,pruritus degree,and pigmentation degree as the duration of treatment increased.Piyanling liniment demonstrated comparable efficacy to Halcinonide solution in reducing skin lesion areas and improving pigmentation in chronic eczema.Furthermore,Piyanling liniment showed superior efficacy in enhancing skin lesions and alleviating pruritus compared to Halcinonide solution.After two courses of treatment,the total effective rates for the Piyanling liniment group and Halcinonide solu-tion group were 91.84%and 81.63%,respectively.The clinical efficacy of Piyanling liniment in the treatment of chronic eczema was superior to that of Halcinonide solution(P=0.001).No adverse drug reactions were reported in either group.Conclusion Piyanling liniment is a safe and effective treatment for chronic eczema.
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