A Compound Vinegar Oral Solution for Promoting Digestion:an Animal Experimental Study
Objective To study the digestion promoting function of a compound Jianweicu oral solu-tion(JW)in mice and rats.Methods 36 SD male rats were randomly divided into 4 dose groups.Rats in the high,medium,low dose groups and solvent control group were orally administered with 10.00,3.33,1.67 ml·kg-1 JW,and distilled water respectively,whose gastric fluid secretion and pepsin were assayed.50 KM male mice were randomly divided into 5 dose groups.Mice in the high,medium,low dose groups,solvent control,model control groups were orally administered with 10.00,3.33,1.67 ml·kg-1 JW,and distilled water respectively before small bowel motility tests were carried out.Results No significant chan-ges in body weight,body weight gain,food intake or food utilization were observed in rats during the 31 days of gavage administration and in mice during the 15 days of gavage administration in any of the weeks.10.00 ml·kg-1 JW significantly increased the total amount of gastric juice,gastric juice discharge,pepsin activity and pepsin discharge in rats,and intestinal motility in mice.3.33 ml·kg-1 JW increased pepsin activity and pepsin excretion,1.67 ml·kg-1 JW increased pepsin activity in rats.Conclusion The compounded JW can help promote digestion.
digestive functionanimal experimentsJianweicu oral liquidpepsingastric juice
NETL
NSTL
万方数据
