脓毒症性凝血病诊疗中国专家共识(2024版)
Chinese expert consensus on the diagnosis and treatment of sepsis-induced coagulopathy(2024 edition)
宋景春 1丁仁彧 2吕奔 3梅恒 4王岗 5张伟 6周静 7郭军 8中国医药教育协会血栓与止血危重病专业委员会 全军重症医学专业委员会
作者信息
- 1. 解放军联勤保障部队第908医院重症医学科,江西 南昌 330002
- 2. 中国医科大学附属第一医院重症医学科,辽宁 沈阳 110001
- 3. 中南大学湘雅二医院血液科,湖南 长沙 410011
- 4. 华中科技大学同济医学院附属协和医院血液科,湖北 武汉 430030
- 5. 西安交通大学第二附属医院重症医学科,陕西 西安 710004
- 6. 解放军联勤保障部队第900医院急诊科,福建 福州 350002
- 7. 四川大学华西医院实验医学科,四川 成都 610041
- 8. 四川大学华西医院重症医学科,四川 成都 610041
- 折叠
摘要
脓毒症性凝血病(SIC)是脓毒症导致的血管内皮损伤和凝血紊乱,是导致脓毒症患者死亡的重要因素.对SIC实现早期诊断和治疗有望改善患者的预后.2019年国际血栓止血学会(ISTH)颁布了首部SIC诊疗指南,但我国尚无相关规范.因此,中国医药教育协会血栓与止血危重病专业委员会和全军重症医学专业委员会共同编写了《脓毒症性凝血病诊疗中国专家共识(2024版)》.该共识包括发病机制、分型、实验室评估、诊断和治疗等5个部分,共14条推荐意见,以便指导相应的临床工作.
Abstract
Sepsis-induced coagulopathy(SIC),a critical and potentially lethal condition arising from sepsis,results in endothelial damage and significant coagulation dysregulation,making it a major factor contributing to mortality among sepsis patients.Early diagnosis and treatment of SIC are expected to improve the prognosis of sepsis patients.In 2019,the International Society on Thrombosis and Hemostasis(ISTH)issued the first guidelines for the diagnosis and treatment of SIC,but there are no corresponding protocols in China.Therefore,Chinese Society of Thrombosis,Hemostasis and Critical Care,Chinese Medicine Education Association,and Chinese People's Liberation Army Professional Committee of Critical Care Medicine jointly formulated the"Chinese Expert Consensus on the Diagnosis and Treatment of Sepsis-induced Coagulopathy(2024 edition)."This consensus includes 5 parts:pathogenesis,classification,laboratory approaches,diagnosis and treatment,with a total of 14 evidence-based recommendations to guide clinical practice.
关键词
脓毒症/凝血病/免疫血栓/血栓炎症/表型/抗凝Key words
sepsis/coagulopathy/immunothrombosis/thromboinflammation/phenotypes/anticoagulation引用本文复制引用
出版年
2024