一种基于三苯胺-噻吩基团的新型荧光探针在藻细胞中检测CN?的应用
A Novel Triphenylamine-thiophene Dyad Fluorescent Probe for Cyanide Detection in Living Algae Cells
文丹 1喻艳华1
作者信息
- 1. 江汉大学 光电化学材料与器件教育部重点实验室,光电材料与技术学院,湖北 武汉 430056
- 折叠
摘要
氰根离子(CN‒)是最具毒性的阴离子之一,一些食用藻类可以从其生活环境中释放氰化物或吸收氰化物,这可能对人类健康造成危害.因此,设计并合成了一种新的荧光探针TI,可用于在活体藻类细胞中检测CN‒.探针TI由三苯胺-噻吩部分和吲哚部分组成,其分子结构中碳氮双键易与CN‒发生亲核加成反应,碳氮双键中共轭π键被打断,探针TI在 473 nm处出现显著的蓝色荧光,从而可用来检测CN‒.探针TI可单一性识别CN‒,最低检测限可达 95.7 nmol/L.最重要的是,探针TI可用于实时检测活藻类细胞和食用藻类中的CN‒.
Abstract
Cyanide(CN‒)is one of the most well-known toxic anions,some edible algae can release cyanide or absorb cyanide from their living environments,which may cause harm to human health.Therefore,we designed and synthesized a novel fluorescent probe TI for CN‒detection in living algae cells.Probe TI was constructed by triphenylamine-thiophene moiety and indolium moiety and exhibited remarkable blue fluorescence at 473 nm upon treatment with cyanide due to the nucleophilic attack of CN‒ on the C=N bond.Moreover,probe TI demonstrated excellent selectivity and sensitivity(LOD 95.7 nmol/L),and a fast responsive time for cyanide detection in an aqueous solution.Most importantly,probe TI could be applied for real-time detection of CN‒in living algae cells and edible algae.
关键词
三苯胺-噻吩/吲哚/CN‒检测/荧光探针/藻细胞Key words
triphenylamine-thiophene/indolium/CN‒detection/fluorescence probe/algae cells引用本文复制引用
基金项目
Jianghan University Science and Technology Special Project(2011KJZX001)
出版年
2024
国家科技期刊平台
NSTL
维普
万方数据