摘要
目的 探讨"双固一通"针法对肥胖型多囊卵巢综合征(PCOS)患者体重、糖脂代谢、月经情况的影响.方法 选取肥胖型PCOS患者65例随机分为"双固一通"组和对照组,分别予以"双固一通"针法及二甲双胍口服治疗,连续治疗 3个月经周期.治疗期间两组均采取生活方式管理.观察两组患者治疗前后糖脂代谢(空腹血糖、胰岛素、HOMA-IR指数、甘油三酯)、体质量指数(BMI)与腰臀比(WHR)和血清激素水平(LH、T、E2、FSH)的变化.结果 "双固一通"组能降低患者血糖、空腹胰岛素水平,HOMA-IR指数、甘油三酯水平、BMI、WHR水平(P<0.05)、及血清LH、T、E2 含量显著降低(P<0.01).改善空腹血糖、胰岛素、甘油三酯、BMI、WHR、LH、E2方面疗效均优于对照组.结论 "双固一通"针法治疗肥胖型PCOS疗效肯定,较二甲双胍更具优势,值得推广应用.
Abstract
Objective To investigate the effect of "Shuanggu Yitong" acupuncture on weight,glucose,and lipid metabolism and menstruation of obese patients with polycystic ovary syndrome(PCOS).Methods 65 obese PCOS patients were randomly divided into the observation group and the control group.The observation group was treated with "shuanggu Yitong" acupuncture + lifestyle management for 3 menstrual cycles,and the control group was given metformin orally + lifestyle management for 3 menstrual cycles.The changes in glucose and lipid metabolism(fasting glucose,insulin,HOMA-IR index,triglyceride),body mass index(BMI),waist-hip ratio(WHR),and serum hormone levels(LH,T,E2,FSH)were compared between the two groups before and after treatment.Results The "Shuanggu Yitong" group can reduce patients'blood sugar,fasting insulin levels,HOMA-IR index,triglyceride levels,BMI,WHR levels(P<0.05),and serum LH,T,and E2 levels significantly reduced(P<0.01).The efficacy in improving fasting blood sugar,insulin,triglycerides,BMI,WHR,LH,and E2 was better than that of the control group.Conclusion The "Shuanggu Yitong" acupuncture method is more effective than metformin in treating obese PCOS and is worthy of promotion and application.
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