Effects of aerobic and resistance exercise on cardiovascular risk in pre-diabetes
Objective To evaluate the effects of aerobic and resistance exercise on glucolipid metabolism levels,disease regression and cardiovascular risk in patients with pre-diabetes.Method Eighty-four patients with pre-diabetes were educated about diabetic diet and were divided into aerobic exercise group(n= 42)and resistance exercise group(n= 42)by randomization method,and both groups were exercised three times a week at moderate intensity for 50 min each time for 12 months of exercise intervention.Changes in glycated hemoglobin(HbA1c),blood glucose and lipid levels were analyzed before,after 6 months and after 12 months of exercise in-tervention.Results Baseline data,HbA1c,fasting glucose,2h PG,TC,TG,HDL-C and LDL-C biochemical indexes were compara-ble between the two groups of patients before exercise intervention(P>0.05).After 6 and 12 months of exercise intervention in both groups,all indexes improved compared with those before the intervention(P<0.05);After 6 months of exercise intervention in both groups,the resistance group reduced 2h PG level better than the aerobic group(P<0.05),and the comparison of HbA1c,fasting glu-cose,TC,TG,HDL-C and LDL-C indexes were not statistically significant(P>0.05).After 12 months of exercise intervention in both groups,the resistance group reduced HbA1c,fasting glucose and 2h PG levels better than the aerobic group(P<0.05),and TC,TG,HDL-C and LDL-C indexes were compared between the two groups without statistical significance(P>0.05).Conclusion Aero-bic and resistance exercise effectively improve blood glucose level and lipid metabolism,delay the development of disease and reduce cardiovascular risk in pre-diabetic patients,and exercise therapy has a positive effect on the conversion to normal in pre-diabetic people.
万方数据
维普
