Effect of stellate ganglion block on ischemia reperfusion injury of lower limb tourniquet
Objective To investigate the effect of stellate ganglion block on lower limb tourniquet ischemia-reperfusion injury and postoperative analgesia.Method 60 patients with lower limb injury surgery admitted to our hospital from February 2020 to June 2022 were selected as research objects,and were divided into control group(n=30)and observation group(n=30)by random number table method.The observation group received stellate ganglion block,while the control group did not receive nerve block.Before applying tourniquet(T0),inflating tourniquet for 10 min(T1),Tourniquet inflated for 30 minutes(T2)Tourniquet inflated for 60 minutes(T3)tourniquet inflated for 90 minutes(T4)Tourniquet loosened HR at 10 min(T5),30 min(T6)and 60 min(T7)after tourniquet re-lease,HR status and expression levels of MDA,SOD and inflammatory factors TNF-α and IL-8,postoperative analgesia,and incidence of postoperative complications(postoperative bleeding,postoperative fever,and atractasis).Results There was no statistical significance in HR at T0,T6 and T7 between the two groups(P>0.05).At T1～T5,HR in the observation group was significantly lower than that in the control group,with statistical significance(P<0.05).There was no significant difference in MDA,SOD,TNF-α and IL-8 between the two groups at T0 time(P>0.05).SOD in the observation group was significantly higher than that in the control group at T7 time,while MDA,TNF-α and IL-8 were lower than that in the control group,with statistical significance(P<0.05).The first analgesic drug taking time of observation group was longer than that of control group,and the frequency of 48 h analgesic pump use was less than that of control group,the difference was statistically significant(P<0.05).The incidence of complications in observation group(3.33%)was lower than that in control group(26.66%),and the difference was statistically significant(P<0.05).Conclusion In the treatment of patients with lower limb tourniquet ischemia reperfusion injury,stellate ganglion block can effectively reduce the pain caused by tour-niquet for patients,avoid organ injury,reduce the possibility of ischemia reperfusion injury,and improve the prognostic effect of the dis-ease.The application effect is significant and worthy of clinical promotion.
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