Status of platinum resistant ovarian cancer recurrence and related factors
Objective To analyze the status and related factors of platinum resistant ovarian cancer recurrence.Method A total of 86 patients with recurrent ovarian cancer admitted to our hospital were selected as research object,they were divided into control group(n=66)and observation group(n=20).Univariate and multivariate logistic regression analysis was conducted to analyze the risk factors of re-current platinum-resistant ovarian cancer.Results Logistic regression analysis:Vascular cancer thrombus,abdominal water≥1 000 ml at initial treatment,ascites with cancer cells,carbohydrate antigen 125(CA125)≥200 U/ml,FIGO staging,albumin(AIB)≤35 g/L,lymphocyte to monocyte ratio(LMR)<5.12,platelet to lymphocyte ratio(PLR)≥124 were the risk of ovarian cancer recurrence risk factor(P<0.05).Conclusion The recurrence of platinum-resistant ovarian cancer is related to vascular cancer embolus,abdominal water volume at initial treatment,cancer cells in ascites,FIGO stage,abnormal HE4,CA125,AIB,LMR,PLR and other factors,which should attract clinical attention and attention,and give early targeted treatment to minimize the recurrence rate.
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