首页|腔镜甲状腺手术与开放手术治疗≤2cm直径甲状腺乳头状癌的效果比较

腔镜甲状腺手术与开放手术治疗≤2cm直径甲状腺乳头状癌的效果比较

扫码查看
目的:探讨腔镜甲状腺手术与开放手术对≤2 cm直径甲状腺乳头状癌的治疗效果.方法:选取临海市中医院普外科 2021 年9 月~2022 年12 月收治的160 例肿瘤病灶最大直径≤2 cm的甲状腺乳头状癌患者为研究对象,依照手术方式的不同,分为对照组与观察组各 80 例.对照组患者采取常规开放手术治疗,观察组患者采取腔镜甲状腺手术治疗,对比两组患者围术期指标、术后疼痛程度、美观度与满意度及手术前与手术 1 d后的炎性因子表达水平,并对比两组患者术后短期并发症发生率.结果:两组患者术后引流量、淋巴结清扫数目比较,差异无统计学意义(P>0.05),观察组患者手术时间明显高于对照组,观察组患者术中出血量、住院时间明显低于对照组,差异有统计学意义(P<0.05);观察组温哥华瘢痕量表(VSS)、视觉模拟量表(VAS)评分明显低于对照组,观察组满意度评分明显高于对照组,差异有统计学意义(P<0.05);两组患者手术前C反应蛋白(CRP)、白细胞介素-2(IL-2)、肿瘤坏死因子-α(TNF-α)水平比较,差异无统计学意义(P>0.05),手术后两组患者CRP、IL-2和TNF-α水平均升高,但观察组升高的程度明显小于对照组,差异有统计学意义(P<0.05);观察组患者术后短期切口出血、声音嘶哑、颈部不适、皮下瘀斑、手足麻木等并发症发生率与对照组比较,差异无统计学意义(P>0.05).结论:腔镜甲状腺手术与开放手术对≤2 cm直径甲状腺乳头状癌均具有良好的治疗效果,但腔镜甲状腺手术与开放手术比较能够进一步减轻手术对患者造成的创伤,淋巴结清扫程度与开放手术相当,能够促进患者术后康复,同时采取腔镜甲状腺手术能够减轻术后炎性因子水平升高现象,安全性较高,并未增加患者短期并发症发生率.
The therapeutic effect of endoscopic thyroidectomy and open surgery on thyroid papillary carcinoma with diameter≤2 cm
Objective To explore the therapeutic effect of endoscopic thyroidectomy and open surgery on thyroid papillary carcino-ma with diameter≤2 cm.Method 160 patients with thyroid papillary carcinoma with the largest diameter of tumor≤2 cm who were admitted to our hospital from September 2021 to December 2022 were selected as the study subjects,and were divided into observation group and control group according to the different surgical methods selected by the patients,with 80 cases in each group.The patients in the control group were treated with conventional open surgery,and the patients in the observation group were treated with endoscopic thyroidectomy.The perioperative indexes,postoperative pain degree,aesthetic degree and satisfaction,the expression level of inflam-matory factors before and 1 day after surgery were compared between the two groups,and the incidence of short-term complications after surgery were compared.Results There was no significant difference in postoperative drainage and number of lymph node dissection be-tween the two groups(P>0.05).The operation time in the observation group were significantly higher than those in the control group.The amount of intraoperative bleeding and hospital stay in the observation group were significantly lower than those in the control group(P<0.05);The Vancounver Scar Scale(VSS)and Visual Analog Scale(VAS)scores were significantly lower in the observation group than in the control group,and the satisfaction scores were significantly higher in the observation group than in the control group(P<0.05);there was no significant difference in the comparison of C-reactive protein(CRP),interleukin-2(IL-2)and tumor necro-sis factor-α(TNF-α)levels between the two groups before surgery(P>0.05),The levels of CRP,IL-2 and TNF-α were elevated in both groups after surgery,but the degree of elevation in the observation group was significantly smaller than that in the control group(P<0.05).The complication rates of short-term postoperative incisional bleeding,hoarseness,neck discomfort,subcutaneous petechi-ae,and numbness of hands and feet in the observation group were not significantly different of the control group,there was no significant difference(P>0.05).Conclusion Endoscopic thyroidectomy and open surgery have good therapeutic effects on thyroid papillary carci-noma with diameter≤2 cm.However,lumpectomy thyroid surgery can further reduce the trauma caused by the surgery compared to open surgery,and the degree of lymphatic clearance is comparable to that of open surgery,and promote the postoperative rehabilitation of patients.At the same time,endoscopic thyroidectomy can reduce the increase of inflammatory factor level after surgery,and has high safety,It does not increase the incidence of short-term complications.

Endoscopic thyroid surgeryOpen surgeryTumor diameterThyroid cancerPapillary carcinomaComplication

刘海舟、张卫峰、张东宝、杨帆帆、陈亮

展开 >

临海市中医院普外科,浙江 临海 317000

腔镜甲状腺手术 开放手术 肿瘤直径 甲状腺癌 乳头状癌 并发症

临海市科技局项目

2021SF21

2024

吉林医学
吉林省人民医院

吉林医学

影响因子:0.926
ISSN:1004-0412
年,卷(期):2024.45(6)
  • 8