Analysis of influencing factors of cognitive dysfunction in patients with chronic obstructive pulmonary dis-ease and sleep apnea
Objective To explore the related factors of cognitive impairment(CI)in patients with chronic obstructive pulmonary disease(COPD)and sleep apnea.Method 40 patients with COPD and sleep apnea in our hospital from September 2022 to February 2023 were selected as research subjects,and smoking,lung function,sleep monitoring,blood gas analysis,blood routine,C-reactive protein,and Montreal Cognitive Assessment Scale(MoCA)were collected.According to the situation of CI,they were divided into 16 cases of non-CI group and 24 cases of CI group,and the relevant influencing factors of CI were discussed.Results Compared with the non-CI group,the proportion of smoking,COPD duration≥5 years,hypoxemia,severe impairment of lung function,AHI index and inflammatory coincidence index in CI group was higher(P<0.05).Conclusion Smoking,COPD duration≥5 years,hypoxemia,se-vere impairment of lung function,AHI index,and inflammatory load index may be high risk factors for cognitive dysfunction in patients with COPD and sleep apnea.
Chronic obstructive pulmonary diseaseSleep apneaCognitive functionAHI indexInflammation load index
NETL
NSTL
万方数据
