Clinical Research on Acupuncture combined with Physical Rehabilitation Treatment of Sepsis-induced My-opathy
Objective To observe the clinical efficacy and mechanism of Yiqi Huoxue Tongluo acupuncture combined with physical rehabilitation in the treatment of sepsis-induced myopathy(SIM).Method Ninety patients with SIM admitted to Foshan Traditional Chinese Medicine Hospital from January 2021 to October 2023 were selected as the research subjects,and they were randomly divided into the control group,the physical rehabilitation group or the observation group,30 patients in each group.All of the groups received basic treatment for sepsis,the physical rehabilitation group received passive or active rehabilitation of limbs,30 minutes each time,twice a day,and the observation group was treated with acupuncture treatment of Yiqi Huoxue Huayu Tongluo method basic on the treatment of the rehabilitation for 7 days.The muscle strength score(MRCs),interleukin-6(IL-6),cross-sectional area of rectus femoris(RFC-SA),acute physiology and chronic health score(APACHEⅡ)and sequential organ failure score(SOFA)were compared before and after treatment among the 3 groups.The length of ICU stay,total length of hospital stay,28-day mortality,and the activity of daily living(ADL)scores of the survivors at 28 days were recorded.Results Compared with before treatment,the IL-6 of the 3 group was signifi-cantly decreased(P<0.05)and the MRCs was significantly increased(P<0.05),the RFCSA of the control group and the physical re-habilitation group were significantly decreased(P<0.05),while there was no significant change in the observation group(P>0.05).Compared with the control group,the IL-6 of the observation group after treatment was significantly reduced(P<0.05),the RFCSA of the observation group and the physical rehabilitation group were significantly larger after treatment(P<0.05),and the MRCs of the ob-servation group were significantly increased(P<0.05).Compared with the physical rehabilitation group,the IL-6,RFCSA and MRCs of the observation group were more significantly improvement(P<0.05).The APACHEⅡ and SOFA scores of the 3 group were signifi-cantly lower than those before treatment(P<0.05).Furthermore,those of the observation group significantly lower than the control group(P<0.05).There was no significant difference between the physical rehabilitation group and the control group(P>0.05).In terms of ICU stay,the physical rehabilitation group and the observation group were significantly shorter than the control group(P<0.05),but there was no significant difference between the observation group and the physical rehabilitation group(P>0.05).In terms of total hospital stay and 28-day mortality,there was no significant difference among the 3 groups(P>0.05).The ADL score of survival patients on the 28th day in the observation group was significantly higher than the other groups(P<0.05),but there was no significant difference between the control group and the physical rehabilitation group(P>0.05).Conclusion In patients with SIM,the physical re-habilitation group can reduce muscle atrophy,and the treatment of acupuncture combined with physical rehabilitation can effectively re-duce the level of inflammation and muscle atrophy,thereby improving muscle strength,shortening the length of ICU stay,and improving the quality of life of surviving patients.
AcupuncturePhysical rehabilitationSepsis-induced myopathyInflammationIntensive care unit-acquired weakness
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