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不同强度康复运动对急性心肌梗死后心功能不全患者的影响

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目的:比较不同强度的康复运动对急性心肌梗死后心功能不全患者获益差异,为指导该类患者行康复运动提供临床依据.方法:选取中国人民解放军联勤保障部队第 908 医院 2021 年 6 月~2023 年 2 月收治的急性心肌梗死急诊经皮冠状动脉介入治疗(PCI)术后合并心功能不全患者为研究对象,随机分为静息组(REST)、低强度训练组(LICT)、中等强度训练组(MICT)和间歇性高强度训练组(HIIT),予不同强度康复运动 24 周,3 次/周,比较左心室射血分数(LVEF)、舒张末期左心室容积(LVEDv)、E峰值、左心房前后径(LA-ap)、N末端脑钠肽前体(NT-proBNP)及 6 min步行试验(6MWT),并随访重大不良心血管事件发生情况.结果:75 例患者纳入研究,其中REST组 18 例、LICT组 19 例、MICT组 17 例、HIIT组 21 例,性别、年龄等临床一般资料及LVEDv、NT-proBNP及 6 MWT等心功能指标四组之间差异无统计学意义(P>0.05).康复训练 24 周后,与REST组比较,行MICT、HIIT的康复运动组LVEDv、LA-ap、NT-proBNP均显著降低,差异有统计学意义(P<0.05),LVEF和E峰值、6 MWT均显著提升,差异有统计学意义(P<0.05);与行MICT组比较,行HIIT组LVEDv进一步显著降低,差异有统计学意义(P<0.05),LVEF、6 MWT进一步显著升高,差异有统计学意义(P<0.05).与REST组比较,行LICT组 6 MWT升高,差异有统计学意义(P<0.05).不良心血管事件发生情况,REST组 7 例、LICT组 6 例、MICT组 2 例、HIIT组 1 例.结论:行MICT、HIIT强度的康复训练方式均能改善急性心肌梗死后合并心功能不全患者的心功能,其中行HIIT训练方式尤为明显,该类患者以间歇性高强度康复训练为宜.
The effect of different intensities of rehabilitation exercise on patients with cardiac dysfunction after acute myocardial infarction
Objective To compare the benefits of different intensities of rehabilitation exercise in patients with cardiac insufficiency after acute myocardial infarction,to provide a clinical basis for guiding rehabilitation exercise for these patients.Method The patients with cardiac dysfunction after emergency operation of acute myocardial infarction admitted to the 908 Hospital of the Joint Support Force of the Chinese People's Liberation Army from June 2021 to February 2023 were selected as the research objects,they were randomly di-vided into the resting(REST)group,low-intensity training(LICT)group,moderate-intensity training(MICT)group and intermittent high-intensity training(HIIT)group,who were given with rehabilitation exercises at different intensities for 24 weeks,three times a week.LVEF,LVEDv,E peak,LA-ap,NT-proBNP and 6-minute walking distance was compared,and the follow-up on the occur-rence of major adverse cardiovascular events was performed.Results A total of 75 patients were included in the study,including 18 pa-tients in the REST group,19 patients in the LICT group,17 patients in the MICT group,and 21 patients in the HIIT group.There was no significant difference between the four groups in terms of general clinical data such as gender and age,as well as cardiac function in-dexes,including LVEDv,NT-proBNP and 6-minute walking distance(P>0.05).After 24 weeks of rehabilitation training,compared with the REST group,LVEDv,LA-ap and NT-proBNP was significantly reduced in the rehabilitation exercise group-MICT group and HIIT group(P<0.05);the LVEF,E peaks and 6-minute walking distance was significantly increased(P<0.05);compared with HI-IT group and MICT group,the LVEDv was further significantly decreased(P<0.05),LVEF and 6-minute walking distance was further significantly increased(P<0.05).Compared with the REST group,the 6-minute walking distance increased in the LICT group.Ad-verse cardiovascular events occurred in 7 cases in the REST group,6 cases in the LICT group,2 cases in the MICT group,and 1 case in the HIIT group.Conclusion In this study,it preliminarily demonstrates that both MICT and HIIT intensive rehabilitation training can improve the cardiac function of patients with cardiac insufficiency after acute myocardial infarction,especially HIIT,which suggests that the intermittent high-intensity rehabilitation training is appropriate for these patients.

Acute myocardial infarctionCardiac rehabilitation exercisesStrength trainingCardiac function

袁方正、王强、肖秋金、许梦阅、王洪如

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中国人民解放军联勤保障部队第 908 医院心内科,江西 南昌 330001

中国人民解放军联勤保障部队第 908 医院超声诊断科,江西 南昌 330001

急性心肌梗死 心脏康复运动 强度训练 心功能

江西省卫生健康委科技计划项目

202211374

2024

吉林医学
吉林省人民医院

吉林医学

影响因子:0.926
ISSN:1004-0412
年,卷(期):2024.45(11)