Effects of pressure and depth of measurement on liver elastography
Objective To evaluate the effect of pressure and measurement depth on Liver Stiffness Measurement(LSM)by Visual Transient Elastography(VTE),and explore the appropriate depth.Method 41 healthy people were randomly selected as research ob-ject.The age,gender,height,body mass index(BMI),subcutaneous fat thickness,history of smoking,drinking,hypertension and diabetes were recorded.Firstly,three groups of LSMs were obtained by placing the probe on the surface of skin and setting the pressure at 2,3,4.Then four groups of LSMs were obtained by setting the detection depth as 1 cm,2 cm,3 cm and 4 cm away from upper liver to the liver capsule according to the Region of Interest(ROI).Results There was no significant difference in LSM when the probe was placed on the skin surface under different pressures(P>0.05).The success rate of different depth detection was statistically significant(P<0.05);the detection success rate of 1 cm and 2 cm away from the liver capsule was higher,and because of the increase of detec-tion depth,the success rate gradually decreased when the distance from liver capsule was 3 cm or 4 cm.There were significant differ-ences in LSM among different measurement depths(P<0.05).With the increase of depth,LSM value increased.There was no signifi-cant correlation between LSM and age,gender,BMI,drinking,hypertension,diabetes,subcutaneous fat thickness and other factors.Conclusion The accuracy and repeatability of liver LSM measurement are both unrelated with the pressure exerted on the skin by the probe.The measurement of liver elasticity by VTE is influenced by the detection depth.It is suggested that the detection depth of measurement should be one centimetre under the liver capsule.
万方数据
维普
