Immunomodulatory Effects of Enzymatic Solution from First-Cut and Regenerated Velvet Antler of Sika Deer
This study aims to investigate the effects of enzymatic lysis of first-cut velvet antler and regenerated velvet antler on immune function of mice.Thirty five 6 weeks old healthy male mice were selected with an average body weight of 20-25 g to divide into seven experimental groups.The control group was gavaged with distilled water.The other six experimental groups named first-cut velvet antler 1,first-cut velvet antler 2 and first-cut velvet antler 3 and regenerated 1,regenerated 2 and regenerated 3,were gavaged with the enzymatic solution prepared from different velvet antler.Each group was gavaged with 0.3 mL per day.The period of intragastric administration lasted 14 days.The blood of mouse eyeballs was taken to detect the content of immune factors in serum after the end of the trial cycle,and the liver index,thymus index and spleen index were calculated after dissection.The results showed that the visceral index and the expression level of immunoglobulin A(IgA),immunoglobulin G(IgG),and immunoglobulin M(IgM)were significantly higher in the experimental group than those in the control group(P＜0.05).The visceral index and modulatory effects of immune factors was higher in the first-cut velvet antler group than those in the regenerated velvet antler group.The experiment proved that immune activity was higher in the first-cut antler group than that in the regenerated velvet antler group.
万方数据
维普
