拉萨市藏族中学生认知功能与海拔高度的关联研究
Association Study Between Cognitive Function and Altitude Among Tibetan Middle School Students in Lhasa
廉启国 1赵文虎 2王延会 2章睿祺 3拉巴桑珠 3邓莉萍 2刘志浩4
作者信息
- 1. 西藏拉萨市疾病预防控制中心(西藏拉萨市卫生监督所),拉萨,850005;上海市生物医药技术研究院,上海,200237
- 2. 西藏拉萨市疾病预防控制中心(西藏拉萨市卫生监督所),拉萨,850005
- 3. 西藏大学医学院,拉萨,850005
- 4. 江苏省疾病预防控制中心(江苏省预防医学科学院),南京,210009;江苏省预防医学会,南京,210009
- 折叠
摘要
目的 探讨拉萨市藏族中学生认知功能与海拔高度的关联,为制定高海拔地区学生的认知能力干预策略提供依据.方法 于 2023 年 11-12 月采用分层随机整群抽样的方法,选取拉萨市海拔 3 590 米、3 760 米、4 285 米三个县出生长大的 1 368 名藏族中学生,采用瑞文推理测验高年级简化版进行问卷调查.结果 本研究中有 26.90%的藏族中学生认知功能较低,其中14岁年龄组、女生、海拔高度较高的中学生认知功能更低,差异均有统计学意义(P<0.05).在控制了班级聚集性、调整了性别和年龄等混杂因素后,多元线性回归分析结果显示,海拔在3 760米、4 285米的藏族中学生认知水平得分低于3 590米的学生.调整性别和年龄等混杂因素后,多因素logistic回归分析结果显示,与海拔3 590 米组的藏族中学生相比,海拔在3 760米组和 4 285米组的认知功能较低.在其他变量取均值的情况下,海拔 4 285米的藏族中学生认知功能低下的概率为 37%.结论 拉萨市藏族青少年的认知功能与海拔高度和性别有关;女生较男生面临更高的认知功能低下风险;海拔越高,认知功能低下的概率越大.
Abstract
Objective To explore the association between cognitive function and altitude among Tibetan middle school students in Lhasa,to provide evidence for the development of cognitive intervention strategies for students in high altitude areas.Methods A total of 1368 Tibetan middle school students in Lhasa City at altitudes of 3590 m,3760 m,and 4285 m were selected by stratified random cluster sampling method from November to December,2023.The Raven's Standard Progressive Matrices(SPM)test was used for questionnaire surveys.Results The prevalence of lower cognitive function were 26.9%,students aged 14,female,residing at higher altitudes had a lower cognitive function(P<0.05).In control of class aggregation,adjusting for confounding factors such as gender and age,multivariate linear regression analysis showed that students at altitudes of 3 760 m and 4 285 m had lower cognitive scores compared to those at 3 590 m.Multivariate logistic regression analysis showed that students at altitudes of 3 760 m and 4 285 m had a lower cognitive function compared to those at 3590 m.With other variables at mean values,the probability of lower cognitive function among students at 4285 m was 0.37(37%).Conclusion The cognitive function among Tibetan students was associated with altitude and gender;female students had a higher risk of cognitive impairment;as increases in altitude,the probability of cognitive impairment among Tibetan students also elevated.
关键词
高海拔/认知水平/藏族中学生/关联研究Key words
High altitude/Cognitive function/Tibetan students/Association study引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据