Study of contrast-enhanced ultrasound combined with Chinese-thyroid imaging,reporting and data system in the diagnosis and biopsy efficiency of thyroid nodules
Objective To investigate the value of Chinese-thyroid imaging,reporting and data system(C-TIRADS)com-bined with contrast-enhanced ultrasound in the diagnosis of thyroid nodules.Methods A total of 413 patients with thyroid nodules(413 nodules)who received ultrasound examination in the Department of Ultrasound Medicine,the First Affiliated Hospital of Guangxi Medical University from January to June 2022 were selected as the study objects.With pathological findings as the"gold standard",all patients were classified by C-TIRADS and combined with contrast-enhanced ultra-sound.The sensitivity,specificity and accuracy of C-TIRADS classification and C-TIRADS classification combined with contrast-enhanced ultrasound were compared.The recommended thyroid biopsy was performed according to the C-TIRADS guideline and the C-TIRADS guideline combined with contrast-enhanced ultrasound,and the biopsy yield of malignant tu-mors,the biopsy rate of malignant tumors and the rate of unnecessary biopsies were calculated and compared respectively.Results The results of C-TIRADS showed 363 benign nodules and 50 malignant nodules.C-TIRADS combined with con-trast-enhanced ultrasound were used to diagnose 267 benign nodules and 146 malignant nodules.The sensitivity,specificity and accuracy of C-TIRADS combined with contrast-enhanced ultrasound in the diagnosis of thyroid cancer were higher than those of C-TIRADS,and the differences were statistically significant(P<0.05).For all nodules,1.0-1.5 cm nodules,the biopsy rate of malignant tumors with C-TIRADS combined with contrast-enhanced ultrasound was lower than that of C-TIRADS alone.For nodules>1.5 cm,the biopsy rate of malignant tumor and unnecessary biopsy rate of C-TIRADS combined with contrast-enhanced ultrasound were lower than that of C-TIRADS alone,the differences were statistically significant(P<0.05).Conclusion The combination of C-TIRADS and contrast ultrasound can improve the ultrasound diagnostic efficiency of thyroid nodules,and contrast ultrasound combined with C-TIRADS can also improve the reliability of recommending thyroid nodules biopsy,in-crease the biopsy yield of malignant nodules,and reduce the unnecessary biopsy rate of benign thyroid nodules.
Thyroid noduleChinese-thyroid imaging,reporting and data systemContrast-enhanced ultrasoundDiag-nostic effectivenessUnnecessary biopsy rate