Comparison of image characteristics between optical coherence tomogra-phy angiography and indocyanine green angiography in patients with polypoid choroid angiopathy
Objective To summarize the image characteristics of optical coherence tomography angiography(OCTA)and indocyanine green angiography(ICGA)in patients with polypoid choroidal angiopathy.Methods By convenient sampling method,50 patients with polypoid choroidal angiopathy who were treated in the Affiliated Eye Hospital of Nanchang University from April 2021 to April 2022 were selected as the research objects.All patients underwent OCTA and ICGA examinations before treatment.The results of ICGA were used as the gold standard,and the results of OCTA and ICGA were compared and analyzed.Results Among the 50 patients,ICGA showed characteristic polypoid lesions in 17 cases,abnormal branch vascular network in 21 cases,abnormal branch vascular network with characteristic polypoid lesions in 10 cases,and no abnormal manifestations due to bleeding occlusion in 2 cases,with a detection rate of 96.00%(48/50).OCTA showed characteristic polypoid lesions in 16 cases,abnormal branch vascular network in 19 cases,and abnormal branch vascular network with characteristic polypoid lesions in 11 cases,the detection rate was 92.00%(46/50).There was no significant difference in the detection rate between the two examination methods(x 2=0.709,P=0.400).Kappa consistency test showed that ICGA and OCTA had high consistency in diagnosing polypoid choroidal vascular disease(Kappa=0.816,P<0.001).The sensitivity,specificity and accuracy of OCTA in the diagnosis of polypoid choroid angiopathy were 97.83%(45/46),75.00%(3/4)and 92.00%(46/50),respectively,based on the ICGA results as the gold standard.Conclusion The consistency of ICGA and OCTA in the diagnosis of polypoid choroidal vascular disease is high.If ICGA shows abnormal branch vascular network,OCTA shows similar findings.In patients with characteristic polypoid lesions on ICGA,obvious strong signal highlights can be seen on OCTA.ICGA and OCTA showed a certain similarity in the shape and location of the lesions.
Polypoid choroidal angiopathyIndocyanine green angiographyOptical coherence tomography angio-graphyImage features