Correlation between serum interleukin and pulmonary artery pressure in patients with chronic obstructive pulmonary disease combined with pul-monary hypertension
Objective To investigate the correlation between serum interleukin(IL)and pulmonary artery pressure in serum of patients with chronic obstructive pulmonary disease(COPD)combined with pulmonary hypertension.Methods Sixty pa-tients with COPD admitted to the Department of Respiratory and Critical Care Medicine,Chest Hospital of Jiangxi Province from January 2022 to February 2023 were retrospectively selected as research objects.They were divided into the control group(30 cases)and the observation group(30 cases)according to whether pulmonary hypertension was combined.The con-trol group was COPD patients,and the observation group was COPD patients with pulmonary hypertension.The expression levels of IL-2,IL-10 and IL-17 in serum of the two groups were compared,and the correlation between IL-2,IL-10 and IL-17 in serum of the observation group and pulmonary artery pressure was analyzed.Results The levels of IL-2 and IL-10 in the observation group were higher than those in the control group,and the differences were statistically significant(P＜0.05).There was no significant difference in serum IL-17 between the two groups(P＞0.05).IL-2 was positively correlated with pulmonary artery pressure(r=0.682,P=0.021),IL-10 was positively correlated with pulmonary artery pressure(r=0.714,P=0.013),and IL-17 was not significantly correlated with pulmonary artery pressure(r=0.171,P=0.152).Conclu-sion IL-2 and IL-10 are relate to the formation of pulmonary hypertension,while IL-17 is not relate to the formation of pul-monary hypertension.
万方数据
维普
