首页|针灸治疗乳腺癌化疗相关性周围神经病变的有效性及安全性的研究

针灸治疗乳腺癌化疗相关性周围神经病变的有效性及安全性的研究

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目的 研究针灸治疗乳腺癌化疗相关性周围神经病变(CIPN)的有效性及安全性。方法 选取2019年2月至2022年10月南昌市人民医院收治的100例乳腺癌CIPN患者作为研究对象,采用随机数字表法将其分为试验组及对照组,各50例。试验组选用温针灸治疗,对照组则开展常规药物联合单纯针刺治疗。比较两组的CIPN情况、功能状态以及生活质量。结果 试验组通用毒性标准分级(NCI-CTC)优于对照组,差异有统计学意义(P<0。05)。试验组治疗后的卡氏功能状态评分(KPS)高于对照组,差异有统计学意义(P<0。05)。试验组治疗后的欧洲癌症治疗研究组织生活质量评估表(EORTCQLQ-C30)评分高于对照组,差异有统计学意义(P<0。05)。结论 温针灸治疗乳腺癌CIPN的效果较佳,且有效改善患者功能状态以及生活质量,值得推广。
Efficacy and safety of acupuncture in treating chemotherapy-associated peripheral neuropathy of breast cancer
Objective To study the efficacy and safety of acupuncture in the treatment of chemotherapy-associated periph-eral neuropathy(CIPN)of breast cancer.Methods A total of 100 patients with CIPN from February 2019 to October 2022 from Nanchang People's Hospital were selected as the research objects.They were divided into experimental group and con-trol group by random number table method,with 50 cases in each group.The experimental group was treated with warm acupuncture,while the control group was treated with conventional drugs combined with simple acupuncture.The CIPN condition,functional status,and quality of life were compared between the two groups.Results The proportion of National Cancer Institute Common Terminology Criteria(NCI-CTC)grade in experimental group was better than that in control group,the difference was statistically significant(P<0.05).After treatment,Karnofsky score(KPS)score of experimental group was higher than control group,the difference was statistically significant(P<0.05).After treatment,European Organization for Reasearch and Treatment of Cancer of Quality of Life Questionnare-Core 30(EORTCQLQ-C30)score of experimental group was higher than control group,the difference was statistically significant(P<0.05).Conclusion Warm acupuncture and moxibustion is effective in the treatment of CIPN of breast cancer,and can effectively improve the functional status and quality of life of patients.It is worth promoting.

Breast cancerChemotherapy-associated peripheral neuropathyAcupunctureEffectivenessSecurity

彭蔷、戈尔舟、陈文艳

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南昌市人民医院乳腺肿瘤内科,江西南昌 330000

中国铁路集团公司南昌局南昌铁路疾病预防控制所预防门诊部,江西南昌 330002

乳腺癌 化疗相关性周围神经病变 针灸 有效性 安全性

江西省卫生健康委科技计划项目

220218642

2024

中国当代医药
中国保健协会 当代创新(北京)医药科学研究院

中国当代医药

影响因子:1.215
ISSN:1674-4721
年,卷(期):2024.31(2)
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