Study on the correlation betueen high signal lesions on DWI and insulin resistance in the distant part of primary cerebral hemorrhage hematoma
Objective To investigate the risk factors of high signal lesions in diffusion weighted imaging in patients with primary cerebral hemorrhage.Methods The clinical data of 132 patients with primary cerebral hemorrhage admitted to Jiu-jiang NO.1 People's Hospital from January 2021 to September 2022 were retrospectively analyzed.The patients were divided into group A(with R-DWILs)and group B(without R-DWILs)according to whether remote-diffusion weighted imaging(R-DWILs)occurred at the distant site of hematoma.The levels of demographic characteristics and hematology indexes were compared between the two groups.Multivariate logistic regression analysis was used to determine the influencing factors of R-DWILs in primary cerebral hemorrhage.Results The age of patients in group A was higher than that in group B,and the difference was statistically significant(P＜0.05).There were no significant differences in gender,diabetes,hypertension,atrial fibrillation,smoking,drinking,time from onset to admission,and hematoma volume between the two groups(P＞0.05).The fasting blood-glucose(FPG),homeostasis model assessment-insulin resistance(HOMA-IR)and neutrophil-lymphocyte ratio(NLR)in group A were higher than those in group B,and the differences were statistically significant(P＜0.05).There were no significant differences in white blood cell count and erythrocyte sedimentation rate between the two groups(P＞0.05).Multivariate logistic regression analysis showed that elder age,high FPG,high HOMA-IR and high NLR were all inde pendent risk factors for R-DWILs in primary cerebral hemorrhage(OR=1.492,2.173,1.686,1.736,95％CI:1.045-1.896,1.356-3.682,1.145-4.371,1.166-3.501,P=0.001,＜0.001,＜0.001,＜0.001).Conclusion Insulin resistance increases the risk of R-DWILs in patients with primary cerebral hemorrhage.
Primary cerebral hemorrhageHigh signal lesionInsulin resistanceDiffusion weighted imaging
万方数据
维普
