中国当代医药2024,Vol.31Issue(2) :70-74.

甲状腺乳头状癌临床特征及颈部淋巴结转移相关危险因素分析

Clinical features of papillary thyroid carcinoma and risk factors related to cervical lymph node metastasis

宋景双 杜勇 黄颖 曾繁余
中国当代医药2024,Vol.31Issue(2) :70-74.

甲状腺乳头状癌临床特征及颈部淋巴结转移相关危险因素分析

Clinical features of papillary thyroid carcinoma and risk factors related to cervical lymph node metastasis

宋景双 1杜勇 1黄颖 1曾繁余1
扫码查看

作者信息

  • 1. 桂林医学院附属医院乳腺甲状腺外科,广西桂林 541000
  • 折叠

摘要

目的 探讨甲状腺乳头状癌(PTC)临床特征及颈部淋巴结转移相关危险因素,为其外科治疗方式提供依据.方法 选取桂林医学院附属医院2018年10月至2022年12月收治的经手术治疗的220例甲状腺乳头状癌患者为研究对象,分析其临床病理特征及颈部淋巴结转移相关危险因素.结果 220例患者中,164例患者发生中央区和(或)侧颈区淋巴结转移(74.55%).单因素分析结果显示,患者的性别、年龄、肿瘤直径、侵犯被膜、浸润性生长、多灶性、肿瘤位于甲状腺上部与颈部淋巴结转移相关(P<0.05);多因素logistic分析结果显示,男性、年龄(<45岁)、肿瘤直径(>1 cm)、肿瘤浸润性生长是PTC颈部淋巴结转移的独立危险因素(P<0.05).结论 对于男性、年龄<45岁,肿瘤直径>1 cm、肿瘤伴浸润性生长的PTC患者,颈部淋巴结转移风险较高,临床上应积极手术干预.

Abstract

Objective To explore the clinical characteristics and risk factors related to cervical lymph node metastasis of papillary thyroid carcinoma(PTC),and provide a basis for its surgical treatment.Methods A total of 220 patients with pap-illary thyroid cancer treated by surgery in the Affiliated Hospital of Guilin Medical University from October 2018 to Decem-ber 2022 were selected as the study objects,and their clinicopathological characteristics and risk factors related to cervical lymph node metastasis were analyzed.Results Among 220 patients,164(74.55%)had lymph node metastasis in the central and/or lateral cervical regions.Univariate analysis showed that gender,age,tumor diameter,invasion of the capsule,invasive growth,multifocal,tumor location in the upper thyroid gland,and cervical lymph node metastasis were correlated(P<0.05).The results of logistic multivariate analysis showed that male,age(<45 years old),tumor diameter(>1 cm),and invasive tumor growth were independent risk factors for cervical lymph node metastasis in PTC(P<0.05).Conclusion For male pa-tients with PTC,who are less than 45 years old,have a tumor diameter greater than 1 cm,and have infiltrative growth,the risk of cervical lymph node metastasis is higher,and active surgical intervention should be taken in clinical practice.

关键词

甲状腺乳头状癌/颈部淋巴结/转移/临床特征/危险因素

Key words

Thyroid papillary carcinoma/Cervical lymph node/Metastasis/Clinical characteristics/Risk factors

引用本文复制引用

基金项目

广西高校中青年教师科研基础能力提升项目(2021KY0493)

出版年

2024
中国当代医药
中国保健协会 当代创新(北京)医药科学研究院

中国当代医药

影响因子:1.215
ISSN:1674-4721
被引量1
参考文献量28
段落导航相关论文