Clinical features of papillary thyroid carcinoma and risk factors related to cervical lymph node metastasis
Objective To explore the clinical characteristics and risk factors related to cervical lymph node metastasis of papillary thyroid carcinoma(PTC),and provide a basis for its surgical treatment.Methods A total of 220 patients with pap-illary thyroid cancer treated by surgery in the Affiliated Hospital of Guilin Medical University from October 2018 to Decem-ber 2022 were selected as the study objects,and their clinicopathological characteristics and risk factors related to cervical lymph node metastasis were analyzed.Results Among 220 patients,164(74.55%)had lymph node metastasis in the central and/or lateral cervical regions.Univariate analysis showed that gender,age,tumor diameter,invasion of the capsule,invasive growth,multifocal,tumor location in the upper thyroid gland,and cervical lymph node metastasis were correlated(P<0.05).The results of logistic multivariate analysis showed that male,age(<45 years old),tumor diameter(>1 cm),and invasive tumor growth were independent risk factors for cervical lymph node metastasis in PTC(P<0.05).Conclusion For male pa-tients with PTC,who are less than 45 years old,have a tumor diameter greater than 1 cm,and have infiltrative growth,the risk of cervical lymph node metastasis is higher,and active surgical intervention should be taken in clinical practice.