首页|甲状腺乳头状癌临床特征及颈部淋巴结转移相关危险因素分析

甲状腺乳头状癌临床特征及颈部淋巴结转移相关危险因素分析

Clinical features of papillary thyroid carcinoma and risk factors related to cervical lymph node metastasis

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目的 探讨甲状腺乳头状癌(PTC)临床特征及颈部淋巴结转移相关危险因素,为其外科治疗方式提供依据.方法 选取桂林医学院附属医院2018年10月至2022年12月收治的经手术治疗的220例甲状腺乳头状癌患者为研究对象,分析其临床病理特征及颈部淋巴结转移相关危险因素.结果 220例患者中,164例患者发生中央区和(或)侧颈区淋巴结转移(74.55%).单因素分析结果显示,患者的性别、年龄、肿瘤直径、侵犯被膜、浸润性生长、多灶性、肿瘤位于甲状腺上部与颈部淋巴结转移相关(P<0.05);多因素logistic分析结果显示,男性、年龄(<45岁)、肿瘤直径(>1 cm)、肿瘤浸润性生长是PTC颈部淋巴结转移的独立危险因素(P<0.05).结论 对于男性、年龄<45岁,肿瘤直径>1 cm、肿瘤伴浸润性生长的PTC患者,颈部淋巴结转移风险较高,临床上应积极手术干预.
Objective To explore the clinical characteristics and risk factors related to cervical lymph node metastasis of papillary thyroid carcinoma(PTC),and provide a basis for its surgical treatment.Methods A total of 220 patients with pap-illary thyroid cancer treated by surgery in the Affiliated Hospital of Guilin Medical University from October 2018 to Decem-ber 2022 were selected as the study objects,and their clinicopathological characteristics and risk factors related to cervical lymph node metastasis were analyzed.Results Among 220 patients,164(74.55%)had lymph node metastasis in the central and/or lateral cervical regions.Univariate analysis showed that gender,age,tumor diameter,invasion of the capsule,invasive growth,multifocal,tumor location in the upper thyroid gland,and cervical lymph node metastasis were correlated(P<0.05).The results of logistic multivariate analysis showed that male,age(<45 years old),tumor diameter(>1 cm),and invasive tumor growth were independent risk factors for cervical lymph node metastasis in PTC(P<0.05).Conclusion For male pa-tients with PTC,who are less than 45 years old,have a tumor diameter greater than 1 cm,and have infiltrative growth,the risk of cervical lymph node metastasis is higher,and active surgical intervention should be taken in clinical practice.

Thyroid papillary carcinomaCervical lymph nodeMetastasisClinical characteristicsRisk factors

宋景双、杜勇、黄颖、曾繁余

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桂林医学院附属医院乳腺甲状腺外科,广西桂林 541000

甲状腺乳头状癌 颈部淋巴结 转移 临床特征 危险因素

广西高校中青年教师科研基础能力提升项目

2021KY0493

2024

中国当代医药
中国保健协会 当代创新(北京)医药科学研究院

中国当代医药

影响因子:1.215
ISSN:1674-4721
年,卷(期):2024.31(2)
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