Research progress of nano-aluminum assisted immunotherapy for allergic asthma
Allergen-specific immunotherapy(AIT)is one of the effective methods for the treatment of allergic diseases.Re-searchers use adjuvants to adsorb allergens,which can prolong the action time of allergens and enhance the effect of helper T cells.At present,the most widely studied adjuvant is aluminum hydroxide adjuvant,but it is found that the local injection site granuloma reaction occurs after its injection into the body.Therefore,in order to find safer and more effective adjuvants,scientists continue to explore and find that nano-aluminum hydroxide has attracted more and more attention in recent stud-ies.The aim of this study is to explore the efficacy and safety of nano-aluminum adjuvant for AIT in allergic asthma mice.