首页|伊尼妥单抗治疗人表皮生长因子受体2阳性转移性乳腺癌伴胃肠功能紊乱1例

伊尼妥单抗治疗人表皮生长因子受体2阳性转移性乳腺癌伴胃肠功能紊乱1例

Inetetamab in the treatment of human epidermal growth factor receptor 2 positive metastatic breast cancer with gastrointestinal dysfunction:a case report

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乳腺癌是女性常见的肿瘤,如今乳腺癌实体肿瘤通过相应的治疗可取得较好的疗效,但人表皮生长因子受体2(HER2)阳性乳腺癌侵袭性较强、恶性程度高,需引起患者及医务人员的重视.本文回顾性分析1例激素受体阴性、HER2阳性伴胃肠功能紊乱的乳腺癌患者诊治经过.患者初诊为局部晚期炎症乳腺癌伴腋窝淋巴结转移,给予新辅助化疗及手术治疗.术后3年后病情进展,予以伊尼妥单抗联合白蛋白紫杉醇,后续伊尼妥单抗单独靶向治疗,病情持续缓解.提示对于HER2阳性晚期乳腺癌,伊尼妥单抗是个很好的单抗类药物选择.
Breast cancer is a common tumor in women.At present,solid tumors of breast cancer can achieve good curative effect through corresponding treatment,but human epidermal growth factor receptor 2(HER2)positive breast cancer is more aggressive and malignant,which needs to attract the attention of patients and medical personnel.A case of breast cancer with hormone receptor-negative,HER2-positive and gastrointestinal dysfunction was retrospectively analyzed.The patient was initially diagnosed with locally advanced inflammatory breast cancer with axillary lymph node metastasis and was treated with neoadjuvant chemotherapy and surgery.When the disease progressed 3 years after surgery,Inetetamab combined with albumin-paclitaxel was given,followed by Inetetamab targeted therapy alone,and the disease continued to be alleviated.It is suggested that Inetetamab is a good choice of monoclonal drugs for HER2-positive advanced breast cancer.

InetetamabMetastatic Breast cancerGastrointestinal dysfunctionHuman epidermal growth factor receptor 2 positive

朱莉丽、付马墨阳、鲁磊、刘湘晨、尚宏清、王冰涛

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北京市海淀医院北京大学第三医院海淀院区乳甲外科,北京 100086

伊尼妥单抗 转移性乳腺癌 胃肠功能紊乱 人表皮生长因子受体2阳性

中国抗癌协会-HER2靶点中国科研基金

CORP-239-M4

2024

中国当代医药
中国保健协会 当代创新(北京)医药科学研究院

中国当代医药

影响因子:1.215
ISSN:1674-4721
年,卷(期):2024.31(3)
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