Application effect of left bundle branch regional pacing in improving car-diac function in patients with right bundle branch block and reduced ejec-tion fraction
Objective To investigate the effect of left bundle branch regional pacing(LBBaP)in improving electrocardio-graphic and cardiac function improvement in patients with right bundle branch block(RBBB)and reduced ejection fraction(LVEF)≤ 35％.Methods Eighty patients with RBBB and LVEF ≤ 35％from the Department of Cardiovascular Medicine of the First People's Hospital of Jiujiang City from February 2020 to August 2022 were selected as study subjects and were di-videdinto control group(40 patients)and experimental group(40 patients)using the random number table method.The con-trol group was given biventricular pacing(Bi-V)and the experimental group was given LBBaP.The left ventricular end-di-astolic diameter(LVDED),left ventricular ejection fraction(LVEF),6-min walk distance(6MWD),standard deviation of NN intervals(SDNN),root mean square of the difference between adjacent NN intervals(rMSSD),standard deviation of mean NN interval(SDANN)every 5 min,ST-T wave alterations,heart failure readmission rate,incidence of death,major complica-tions(cardiac perforation,pericardial effusion,malignant arrhythmia,sudden cardiac death and acute myocardial infarction)were compared between the two groups before and after treatment.Results There were no significant differences in LVDED,LVEF and 6MWD between the two groups before treatment(P＞0.05).After treatment,LVDED of patients in both groups was lower than before treatment in this group,LVEF was higher than before treatment in this group,and 6MWD was longer than before treatment in this group,and the differences were statistically significant(P＜0.05).The LVDED in the experi-mental group was lower than that in the control group after treatment,the LVEF was higher than that in the control group,and the 6MWD was longer than that in the control group,with statistically significant differences(P＜0.05).The ST-T wave alteration rate in the experimental group was higher than that in the control group,and SDNN,rMSSD and SDANN were lower than those in the control group,and the differences were statistically significant(P＜0.05).The readmission rate,com-plication rate and mortality rate of heart failure in the experimental group were lower than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion Left bundle branch regional pacing can effectively improve cardiac function and electrocardiograph indexes,reduce the readmission rate,complication rate and mortality rate of heart failure,and is worth promoting.
Left bundle branch region pacingRight bundle branch blockEjection fractionElectrocardiogramCardiac function improvement
万方数据
维普
