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胃窦横截面积指导老年重症患者肠内营养治疗的临床价值

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目的 探讨应用胃窦横截面积指导老年重症患者肠内营养治疗的临床价值。方法 选取2020年1月至2022年12月在兰州市第一人民医院重症医学科住院的236例老年(年龄≥65岁)重症患者作为研究对象,根据住院先后顺序设置研究对象序号,采用奇偶数方法进行分组,以奇数作为超声组(118例),以偶数作为常规组(118例)。超声组通过胃窦横截面积来指导肠内营养支持治疗,当胃窦横截面积≥709。2 mm2时,停止肠内营养4 h,再进行胃窦横截面积测量,若<709。2 mm2,再进行肠内营养。常规组通过胃残余量来指导肠内营养支持治疗,当胃残量≥200 ml时,停止肠内营养4h,再进行胃残量测定,若明显减少,再进行肠内营养。比较两组患者的血清白蛋白、肠内营养量、肠内营养达标时间、住ICU时间、住院总费用、死亡率,并比较两组患者在治疗过程中发生喂养中断率、返流、误吸、腹泻、肝功能不全、消化道出血、肠梗阻的发生率。结果 两组患者治疗前的血清白蛋白、肠内营养量比较,差异无统计学意义(P>0。05)。两组患者治疗第7天的血清白蛋白高于本组第5天,第5天的血清白蛋白高于本组第3天,第3天的血清白蛋白高于本组第1天,差异有统计学意义(P<0。05);超声组治疗第1、3、5、7天的血清白蛋白高于常规组,差异有统计学意义(P<0。05)。两组患者治疗第7天的肠内营养量高于本组第5天,第5天的肠内营养量高于第3天,第3天的肠内营养量高于第2天,第2天的肠内营养量高于第1天,差异有统计学意义(P<0。05);超声组治疗第1、2、3、5、7天的肠内营养量高于常规组,差异有统计学意义(P<0。05)。超声组的喂养中断率、肠梗阻发生率、病死率、住院总费用低于常规组,肠内营养量达标时间短于常规组,差异有统计学意义(P<0。05)。两组患者反流、误吸、腹泻、肝功能不全、消化道出血的发生率比较,差异无统计学意义(P>0。05);超声组的并发症总发生率低于常规组,差异有统计学意义(P<0。05)。结论 通过胃窦横截面积指导老年重症患者肠内营养支持治疗具有重要的临床价值,可更快达到喂养目标,更早改善低蛋白血症,减少喂养中断率,减少各种并发症的发生,减少住院总费用及病死率,为老年重症患者肠内营养支持治疗提供一定的临床理论依据。
Clinical value of gastroantrum cross-sectional area to guide enteral nutri-tion in elderly patients with severe disease
Objective To explore the clinical value of applying the cross-sectional area of gastric antrum to guide enteral nutrition in elderly patients with severe disease.Methods A total of 236 elderly patients(aged≥65 years)who were hospi-talized in the Department of Intensive Care Medicine of Lanzhou First People's Hospital from January 2020 to December 2022 were selected as the study objects.The study objects were assigned serial numbers according to the order of hospital-ization,and were divided into groups with odd numbers as the ultrasound group(118 cases),even numbers were taken as routine group(118 cases).In the ultrasound group,enteral nutrition support treatment was guided by the cross-sectional area of the antrum.When the cross-sectional area of the antrum was greater than 709.2 mm2,enteral nutrition was stopped for 4 h and then measured.When the cross-sectional area of the antrum was less than 709.2 mm2,enteral nutrition was performed again.In the conventional group,enteral nutri-tion support therapy was guided by gastric residual volume.When gastric residual volume was ≥200 ml,enteral nu-trition was stopped for 4 h,and then gastric residual vol-ume was measured.If it was significantly reduced,enteral nutrition was performed again.The serum albumin,enteral nutrition,enteral nutrition standard time,ICU stay time,total hospitalization cost and mortality of the two groups were compared,and the incidence of feeding interruption rate,regurgita-tion,aspiration,diarrhea,liver insufficiency,gastrointestinal bleeding and intestinal obstruction were compared between the two groups.Results There were no significant differences in serum albumin and enteral nutrition between the two groups before treatment(P>0.05).The serum albumin of the two groups on the 7th day of treatment was higher than that on the 5th day,the serum albumin of the 5th day was higher than that on the 3rd day,and the serum albumin of the 3rd day was higher than that on the 1st day,with statistical significance(P<0.05).The serum albumin of ultrasound group at 1st,3rd,5th and 7th day was higher than that of conventional group,and the difference was statistically significant(P<0.05).The enteral nutri-tion amount on the 7th day of treatment in two groups was higher than that on the 5th day,the enteral nutrition amount on the 5th day was higher than that on the 3rd day,the enteral nutrition amount on the 3rd day was higher than that on the 2nd day,and the enteral nutrition amount on the 2nd day was higher than that on the 1st day,the differences were statistically significant(P<0.05).The enteral nutrition in ultrasound group at the 1st,2ndd,3rd,5th and 7th day was higher than that in conventional group,and the difference was statistically significant(P<0.05).The feeding interruption rate,incidence of intestinal ob-struction,mortality and total hospitalization cost in ultrasound group were lower than those in conventional group,and the time to reach the standard of enteral nutrition was shorter than that in conventional group,the differences were statistically significant(P<0.05).There were no significant differences in the incidence of reflux,aspiration,diarrhea,liver insufficiency and gastrointestinal bleeding between the two groups(P>0.05).The total incidence of complications in ultrasound group was lower than that in conventional group,and the difference was statistically significant(P<0.05).Conclusion It has important clinical value to guide the enteral nutrition support treatment of elderly patients with severe diseases through the cross-sectional area of the gastric antrum,which can achieve the feeding goal faster,improve hypoproteinemia earlier,re-duce the rate of feeding interruption,reduce the occurrence of various complications,reduce the total hospitalization cost and mortality,and provide certain clinical theoretical basis for the enteral nutrition support treatment of elderly patients with severe diseases.

Antrum cross-sectional areaEnteral nutrition therapyCritically ill elderly patientsPrognosis

黄焕源、班丽红、王延震、栾静、雷步博

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兰州市第一人民医院检验科,甘肃兰州 730050

兰州市第一人民医院重症医学科,甘肃兰州 730050

胃窦横截面积 肠内营养治疗 老年重症患者 预后

甘肃省兰州市人才创新创业项目

2019-RC-67

2024

中国当代医药
中国保健协会 当代创新(北京)医药科学研究院

中国当代医药

影响因子:1.215
ISSN:1674-4721
年,卷(期):2024.31(4)
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