One case of chronic lymphocytic leukemia complicated with nephrotic syndrome and acute renal insufficiency and literature review
This study reports a case diagnosed with chronic lymphocytic leukemia(CLL)for 2 years,with nephrotic syn-drome as the initial presentation.Due to the initial refusal of glucocorticoids,the patient was given Cyclophosphamide intra-venous drip and then Methylprednisolone treatment for acute renal insufficiency.The effects of Methylprednisolone and Cy-clophosphamide on the patient's lymphocytes were carefully observed,especially the sudden rise of lymphocytes was given timely and reasonable symptomatic treatment in the induced remission period of the disease.After active treatment,the pa-tient had complete remission of kidney disease.This paper also summarized the treatment options for CLL complicated with nephropathy through literature review,and analyzed that whether there is a causal relationship between CLL and nephropa-thy and whether CLL needs treatment determines the treatment strategy for kidney disease to a large extent,and confirmed the positive effect of glucocorticoids in patients with CLL complicated with nephrotic syndrome.In order to provide reference for clinical diagnosis and treatment of such diseases.
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