Objective To explore the correlation between the telomerase reverse transcriptase(TERT)gene rs2075786 and rs2736100 polymorphisms and the Han Chinese population in longevity in Hezhou.Methods A total of 58 individuals from the Han Chinese population in Hezhou were selected as the research subjects,including 30 individuals in the control group and 28 individuals in the longevity group.The gene typing of the TERT gene rs2075786 and rs2736100 polymorphisms was determined using sequencing methods.The association between the haplotypes constructed by the TERT gene rs2075786 and rs2736100 polymorphisms and longevity was investigated.Results There were no statistically significant differences in the gene and allele frequencies distribution of the TERT gene rs2075786 and rs2736100 polymorphisms between the two groups(P＞0.05).The haplotypes constructed by the TERT gene rs2075786 and rs2736100 polymorphisms were not associ-ated with longevity in the Hezhou Han Chinese population(P＞0.05).Conclusion No correlation was found between the TERT gene rs2075786 and rs2736100 polymorphisms and the Han Chinese population in longevity in Hezhou.
维普
万方数据