中国当代医药2024,Vol.31Issue(6) :41-44.

德谷胰岛素利拉鲁肽注射液与重组甘精胰岛素注射液治疗2型糖尿病的效果比较

Comparison of the effect of Insulin Degludec Liraglutide Injection and Recombinant Insulin Glargine Injection in the treatment of type 2 dia-betes mellitus

张琳琳
中国当代医药2024,Vol.31Issue(6) :41-44.

德谷胰岛素利拉鲁肽注射液与重组甘精胰岛素注射液治疗2型糖尿病的效果比较

Comparison of the effect of Insulin Degludec Liraglutide Injection and Recombinant Insulin Glargine Injection in the treatment of type 2 dia-betes mellitus

张琳琳1
扫码查看

作者信息

  • 1. 辽宁省健康产业集团铁煤总医院内分泌科,辽宁铁岭 112700
  • 折叠

摘要

目的 比较德谷胰岛素利拉鲁肽注射液与重组甘精胰岛素注射液治疗2型糖尿病的效果.方法 选取2021年10月至2022年12月辽宁省健康产业集团铁煤总医院内分泌科收治的70例2型糖尿病患者作为研究对象,采用计算机随机数字表法将其分为研究组(n=35)与常规组(n=35).研究组患者应用德谷胰岛素利拉鲁肽注射液联合阿卡波糖治疗,常规组患者应用重组甘精胰岛素注射液联合阿卡波糖治疗.比较两组患者的血糖、不良反应、满意度以及临床各项指征.结果 治疗后,研究组的空腹血糖(FPG)、餐后2h血糖(2hPG)、糖化血红蛋白(HbA1c)均低于常规组,差异有统计学意义(P<0.05);研究组患者的总满意度高于常规组,差异有统计学意义(P<0.05);研究组患者的不良反应总发生率低于常规组,差异有统计学意义(P<0.05);研究组的血糖达标时间短于常规组,低血糖次数少于常规组,差异有统计学意义(P<0.05).结论 德谷胰岛素利拉鲁肽注射液联合阿卡波糖治疗2型糖尿病患者,可以有效地控制患者的血糖水平,提高患者的满意度,促进其恢复,减少不良反应的发生,值得临床推广应用.

Abstract

Objective To compare the effect of Insulin Degludec Liraglutide Injection and Recombinant Insulin Glargine Injection in the treatment of type 2 diabetes mellitus.Methods A total of 70 patients with type 2 diabetes admitted to the Department of Endocrinology,Liaoning Health Industry Group Iron Coal General Hospital from October 2021 to December 2022 were selected as the research objects,and they were divided into study group(n=35)and conventional group(n=35)by computer random number method.Patients in the study group were treated with Insulin Degludec Liraglutide Injection com-bined with Acarbose,and patients in the conventional group were treated with Recombinant Insulin Glargine Injection com-bined with Acarbose.The blood glucose,adverse reactions,satisfaction and clinical indications were compared between the two groups.Results After treatment,the fasting plasma glucose(FPG),2-hour postprandial plasma glucose(2 h PG)and glycosylated hemoglobin(HbA1c)of the study group were lower than those of the conventional group,and the differences were statistically significant(P<0.05).The total satisfaction of patients in the study group was higher than that in the con-ventional group,and the difference was statistically significant(P<0.05).The total incidence of adverse reactions in the study group was lower than that in the conventional group,and the difference was statistically significant(P<0.05).The time of blood glucose reaching the standard in the study group was shorter than that in the routine group,and the number of hy-poglycemia was less than that in the routine group,and the differences were statistically significant(P<0.05).Conclusion Insulin Degludec Liraglutide Injection combined with Acarbose in the treatment of patients with type 2 diabetes mellitus can effectively control the blood glucose level of patients,improve the satisfaction of patients,promote their recovery,and reduce the occurrence of adverse reactions,which is worthy of clinical application.

关键词

德谷胰岛素利拉鲁肽注射液/阿卡波糖/2型糖尿病/血糖/应用价值

Key words

Insulin Degludec Liraglutide Injection/Acarbose/Type 2 diabetes mellitus/Blood glucose/Application value

引用本文复制引用

出版年

2024
中国当代医药
中国保健协会 当代创新(北京)医药科学研究院

中国当代医药

影响因子:1.215
ISSN:1674-4721
参考文献量21
段落导航相关论文