According to global cancer statistics,lung cancer is still the highest mortality of malignant tumors,of which non-small cell lung cancer accounts for about 85％of the total number of lung cancers.Tumor-treating fields is a safe and effective local anti-tumor therapy.It can play an anti-tumor role by interfering with mitosis,causing DNA damage,inhibit-ing cell migration,increasing cell membrane permeability,improving the ability to penetrate the blood-brain barrier,induc-ing anti-tumor immunity and other mechanisms,and play a synergistic role with chemotherapy,radiotherapy,immunothera-py and other anti-tumor therapies.This article will focus on the mechanism of tumor-treating fields,its clinical research in non-small cell lung cancer or non-small cell lung cancer brain metastases,hoping to provide new ideas for the treatment of non-small cell lung cancer.
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